AbstractRetinoic acid (RA) plays a necessary role in limb development and regeneration, but the precise mechanism by which it acts during these processes is unclear. The role of RA in limb regeneration was first highlighted by the remarkable effect that it has on respecifying the proximodistal axis of the regenerating limb so that serially repeated limbs are produced. To facilitate the study of RA signaling during development and then during regeneration of the same structure we have turned to the axolotl, the master of vertebrate regeneration, and generated transgenic animals that fluorescently report RA signaling in vivo. Characterization of these animals identified an anterior segment of the developing embryo where RA signaling occurs re...
The Mexican Axolotl is able to regenerate missing limb structures in any position along the limb axi...
AbstractThe capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of...
Retinoic Acid (RA) is a vitamin A derivative with severe teratogenic properties. RA is essential for...
We know little about the control of positional information (PI) during axolotl limb regeneration, wh...
Salamanders are capable of regenerating amputated limbs by generating a mass of lineage-restricted c...
Retinoic acid (RA) is a morphogen that functions as a patterning agent in vertebrate development. I...
AbstractBackground: The regenerating limb of urodele amphibians is an important system for evaluatin...
Background: The regenerating limb of urodele amphibians is an important system for evaluating the ef...
117 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1987.Amphibian limb regeneration b...
AbstractIn the developing chick limb bud, retinoic acid (RA) has a striking effect on anteroposterio...
SummaryThe vitamin A metabolite retinoic acid (RA) provides patterning information during vertebrate...
Salamanders are unique among adult vertebrates in their ability to regenerate complex body structure...
The mechanisms by which cells obtain instructions to precisely re-create the missing parts of an org...
Ectopic retinoic acid (RA) has been hypothesized to reprogram the positional identity of cells in de...
The vitamin A metabolite retinoic acid (RA) provides patterning information during vertebrate embryo...
The Mexican Axolotl is able to regenerate missing limb structures in any position along the limb axi...
AbstractThe capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of...
Retinoic Acid (RA) is a vitamin A derivative with severe teratogenic properties. RA is essential for...
We know little about the control of positional information (PI) during axolotl limb regeneration, wh...
Salamanders are capable of regenerating amputated limbs by generating a mass of lineage-restricted c...
Retinoic acid (RA) is a morphogen that functions as a patterning agent in vertebrate development. I...
AbstractBackground: The regenerating limb of urodele amphibians is an important system for evaluatin...
Background: The regenerating limb of urodele amphibians is an important system for evaluating the ef...
117 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1987.Amphibian limb regeneration b...
AbstractIn the developing chick limb bud, retinoic acid (RA) has a striking effect on anteroposterio...
SummaryThe vitamin A metabolite retinoic acid (RA) provides patterning information during vertebrate...
Salamanders are unique among adult vertebrates in their ability to regenerate complex body structure...
The mechanisms by which cells obtain instructions to precisely re-create the missing parts of an org...
Ectopic retinoic acid (RA) has been hypothesized to reprogram the positional identity of cells in de...
The vitamin A metabolite retinoic acid (RA) provides patterning information during vertebrate embryo...
The Mexican Axolotl is able to regenerate missing limb structures in any position along the limb axi...
AbstractThe capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of...
Retinoic Acid (RA) is a vitamin A derivative with severe teratogenic properties. RA is essential for...