High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells.BackgroundPeritoneal fibrosis is a serious complication in long-term continuous ambulatory peritoneal dialysis (CAPD) patients, but the underlying mechanism is not well understood. Since high glucose activates the p38 mitogen-activated protein kinase (MAPK) pathway in various kinds of cells, and because mesothelial cells are always exposed to high glucose dialysate, we examined the activity and expression of p38 MAPK members in cultured human peritoneal mesothelial cells (HPMCs) under high glucose conditions.MethodsHPMCs were isolated from omentum and subcultured. After serum restriction, HPMCs were exposed to 5.6 mmol/L glucose (low glucose), 5.6 mmo...
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothel...
OBJECTIVE: To investigate the effect of high glucose and spent peritoneal dialysate on the transform...
Peritoneal dialysis is an efficient renal replacement therapy for patients with end-stage kidney dis...
BACKGROUND: Peritoneal fibrosis is a serious complication in long-term continuous ambulatory perito...
High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells.Backgroun...
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothel...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
Worldwide 100,000 people are dependent on peritoneal dialysis (PD) for treatment of end-stage renal ...
Worldwide 100,000 people are dependent on peritoneal dialysis (PD) for treatment of end-stage renal ...
BACKGROUND: Peritoneal fibrosis (PF), a serious problem in long-term continuous ambulatory peritonea...
High glucose levels inhibit focal adhesion kinase-mediated wound healing of rat peritoneal mesotheli...
High glucose levels inhibit focal adhesion kinase-mediated wound healing of rat peritoneal mesotheli...
Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expre...
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothel...
OBJECTIVE: To investigate the effect of high glucose and spent peritoneal dialysate on the transform...
Peritoneal dialysis is an efficient renal replacement therapy for patients with end-stage kidney dis...
BACKGROUND: Peritoneal fibrosis is a serious complication in long-term continuous ambulatory perito...
High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial cells.Backgroun...
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothel...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infec...
Worldwide 100,000 people are dependent on peritoneal dialysis (PD) for treatment of end-stage renal ...
Worldwide 100,000 people are dependent on peritoneal dialysis (PD) for treatment of end-stage renal ...
BACKGROUND: Peritoneal fibrosis (PF), a serious problem in long-term continuous ambulatory peritonea...
High glucose levels inhibit focal adhesion kinase-mediated wound healing of rat peritoneal mesotheli...
High glucose levels inhibit focal adhesion kinase-mediated wound healing of rat peritoneal mesotheli...
Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expre...
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothel...
OBJECTIVE: To investigate the effect of high glucose and spent peritoneal dialysate on the transform...
Peritoneal dialysis is an efficient renal replacement therapy for patients with end-stage kidney dis...