Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease
[[abstract]]Stem cells are self-renewable cells with the differentiation capacity to develop intosom...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be ...
The development of human embryonic stem cell technology1 and the ability to differentiate these plur...
The development of human embryonic stem cell technology1 and the ability to differentiate these plur...
Human pluripotent stem cells (hPSCs) have the capacity to differentiate into any of the hundreds of ...
Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to gener...
In the field of regenerative medicine, the development of induced pluripotent stem (iPS) cells may r...
In the field of regenerative medicine, the development of induced pluripotent stem (iPS) cells may r...
Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to gener...
Traditionally, human disorders were studied using animal models or somatic cells taken from patient...
Recent advances in cellular reprogramming and stem cell biology have opened up unique opportunities ...
Differentiated cells can be reprogrammed to pluripotency and other cell fates by treatment with defi...
The derivation of human embryonic cells (hESCs) from human blastocysts represents one of the milesto...
[[abstract]]Stem cells are self-renewable cells with the differentiation capacity to develop intosom...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be ...
The development of human embryonic stem cell technology1 and the ability to differentiate these plur...
The development of human embryonic stem cell technology1 and the ability to differentiate these plur...
Human pluripotent stem cells (hPSCs) have the capacity to differentiate into any of the hundreds of ...
Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to gener...
In the field of regenerative medicine, the development of induced pluripotent stem (iPS) cells may r...
In the field of regenerative medicine, the development of induced pluripotent stem (iPS) cells may r...
Reprogramming of human somatic cells uses readily accessible tissue, such as skin or blood, to gener...
Traditionally, human disorders were studied using animal models or somatic cells taken from patient...
Recent advances in cellular reprogramming and stem cell biology have opened up unique opportunities ...
Differentiated cells can be reprogrammed to pluripotency and other cell fates by treatment with defi...
The derivation of human embryonic cells (hESCs) from human blastocysts represents one of the milesto...
[[abstract]]Stem cells are self-renewable cells with the differentiation capacity to develop intosom...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
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