Electrochemical study and application on rutin at chitosan/graphene films modified glassy carbon electrode

AbstractGraphene (G) was dispersed into 0.5% chitosan (Chit) solution, then the composite films were coated on glassy carbon electrode (GCE), the electrochemical behavior of rutin on a Chit/G modified GCE was investigated and the electrochemical parameters of rutin were calculated. Rutin effectively accumulated on the Chit/G/GCE and caused a pair of redox peaks at around 408mV and 482mV (vs. SCE) in 0.1M phosphate buffer solution (pH 4.0). Under optimized conditions, the anodic peak current was linear to the rutin concentration in the range of 5×10−7–1.04×10−5M. The regression equation was: y=9.9219x–0.0025, r= 0.9958. The proposed method was successfully used for the determination of rutin content in tablet samples with satisfactory results