SummaryA denatured protein chain can find its well-ordered three-dimensional structure, the native state, in under a second, using only the information contained in the sequence. For researchers, however, the prediction of structures from sequences is a hard problem, so they are now recruiting all the help they can get, including idle computers and game consoles, game players, and little hints from evolution. Michael Gross reports
While all the information required for the folding of a protein is contained in its amino acid seque...
Connecting the dots among the amino acid sequence of a protein, its structure, and its function rema...
Protein folding is an important area of research in bioinformatics and molecular biology. The proces...
SummaryA denatured protein chain can find its well-ordered three-dimensional structure, the native s...
Proteins are the essential agents of all living systems. Even though they are synthesized as linear ...
People exert significant amounts of problem solving effort playing computer games. Simple image- and...
In this issue of Structure, Herges and Wenzel (2005) describe a structure-based force field that, wh...
Deriving the structure of a protein from only its DNA sequence is theoretically possible, but the co...
AbstractWith the burgeoning number of protein sequences now appearing as a result of all the genome ...
Fifty years ago, the structures of the alpha-helix, the beta-sheet, the alpha-helical coiled coil an...
It should be possible to predict the fold of a protein into its native conformation, once we are giv...
AbstractIt should be possible to predict the fold of a protein into its native conformation, once we...
• Protein folding is concerned with the process of the protein taking its three dimensional shape. •...
Summary: Motivation Predicting the native state of a protein has long been considered a gateway pro...
One of the grand challenges in computational biology is the prediction of the three-dimensional stru...
While all the information required for the folding of a protein is contained in its amino acid seque...
Connecting the dots among the amino acid sequence of a protein, its structure, and its function rema...
Protein folding is an important area of research in bioinformatics and molecular biology. The proces...
SummaryA denatured protein chain can find its well-ordered three-dimensional structure, the native s...
Proteins are the essential agents of all living systems. Even though they are synthesized as linear ...
People exert significant amounts of problem solving effort playing computer games. Simple image- and...
In this issue of Structure, Herges and Wenzel (2005) describe a structure-based force field that, wh...
Deriving the structure of a protein from only its DNA sequence is theoretically possible, but the co...
AbstractWith the burgeoning number of protein sequences now appearing as a result of all the genome ...
Fifty years ago, the structures of the alpha-helix, the beta-sheet, the alpha-helical coiled coil an...
It should be possible to predict the fold of a protein into its native conformation, once we are giv...
AbstractIt should be possible to predict the fold of a protein into its native conformation, once we...
• Protein folding is concerned with the process of the protein taking its three dimensional shape. •...
Summary: Motivation Predicting the native state of a protein has long been considered a gateway pro...
One of the grand challenges in computational biology is the prediction of the three-dimensional stru...
While all the information required for the folding of a protein is contained in its amino acid seque...
Connecting the dots among the amino acid sequence of a protein, its structure, and its function rema...
Protein folding is an important area of research in bioinformatics and molecular biology. The proces...
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