SummaryA new study shows that protein kinase A (PKA) activity establishes a signaling loop that governs protrusion–retraction cycles in migrating cells. PKA activity near the leading edge of protrusions phosphorylates RhoA and inhibits its activity via increased association with RhoGDI
Abstract Background Cell migration is essential for development and tissue repair, but it also contr...
AbstractRho GTPases control signal transduction pathways that link cell surface receptors to a varie...
Metastasis, initially driven by cells migrating and invading through the local environment, leads to...
SummaryA new study shows that protein kinase A (PKA) activity establishes a signaling loop that gove...
cAMP-dependent protein kinase A (PKA) is important in processes requiring localized cell protrusion,...
Cellular migration is a cornerstone of many biological processes, from the creation and repair of co...
Cell migration requires establishment and maintenance of directional polarity, which in turn require...
Historically, the cAMP-dependent protein kinase (PKA) has a paradoxical role in cell motility, havin...
AbstractA wide variety of soluble signaling substances utilize the cyclic AMP-dependent protein kina...
Historically, the cAMP-dependent protein kinase (PKA) has a paradoxical role in cell motility, havin...
AbstractA wide variety of soluble signaling substances utilize the cyclic AMP-dependent protein kina...
Cell migration requires a precise temporal and spatial coordination of several processes which allow...
Cell migration plays an important role in development and the immune system, and the signaling pathw...
Cell migration plays an important role in development and the immune system, and the signaling pathw...
Background: Cell migration is essential for development and tissue repair, but it also contributes t...
Abstract Background Cell migration is essential for development and tissue repair, but it also contr...
AbstractRho GTPases control signal transduction pathways that link cell surface receptors to a varie...
Metastasis, initially driven by cells migrating and invading through the local environment, leads to...
SummaryA new study shows that protein kinase A (PKA) activity establishes a signaling loop that gove...
cAMP-dependent protein kinase A (PKA) is important in processes requiring localized cell protrusion,...
Cellular migration is a cornerstone of many biological processes, from the creation and repair of co...
Cell migration requires establishment and maintenance of directional polarity, which in turn require...
Historically, the cAMP-dependent protein kinase (PKA) has a paradoxical role in cell motility, havin...
AbstractA wide variety of soluble signaling substances utilize the cyclic AMP-dependent protein kina...
Historically, the cAMP-dependent protein kinase (PKA) has a paradoxical role in cell motility, havin...
AbstractA wide variety of soluble signaling substances utilize the cyclic AMP-dependent protein kina...
Cell migration requires a precise temporal and spatial coordination of several processes which allow...
Cell migration plays an important role in development and the immune system, and the signaling pathw...
Cell migration plays an important role in development and the immune system, and the signaling pathw...
Background: Cell migration is essential for development and tissue repair, but it also contributes t...
Abstract Background Cell migration is essential for development and tissue repair, but it also contr...
AbstractRho GTPases control signal transduction pathways that link cell surface receptors to a varie...
Metastasis, initially driven by cells migrating and invading through the local environment, leads to...
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