Effects of aerobic and resistance training of long duration on pro- and anti-inflammatory cytokines in rats

Silva, C.M.S.
Vieira-Junior, R.C.
Trombeta, J.C.R.
Lima, T.R.
Fraga, G.A.
Sena, M.S.
Ávila, E.T.P.
Tibana, R.A.
Prestes, J.
Navalta, J.W.
Voltarelli, F.A.

Open link

Publication date

September 2016

DOI

10.1016/j.ramd.2016.02.005

Publisher

Consejería de Turismo y Deporte de la Junta de Andalucía. Published by Elsevier España, S.L.U.

Abstract

AbstractObjectiveTo determine possible changes in serum concentrations of pro- and anti-inflammatory cytokines of eutrophic rats subjected to aerobic or resistance physical training.MethodsThis study examined serum concentrations of TNF-α, IFN-γ, IL-6, IL-10 and IL-1-β in rats that performed aerobic or resistance training for 16 weeks. Thirty-five Wistar rats (male adult) were divided into three groups: Control Group (CG), Aerobic Group (AG) and Resistance Group (RG). Rats were sacrificed 48h after the final training session. Serum concentrations of cytokines were analysed by ELISA.ResultsTNF-α levels were higher in the RG, followed by the AG and CG groups (p<0.001). IFN-γ and IL-10 levels were not significantly different between groups (p=...