AbstractAerolysin, a virulence factor secreted by Aeromonas hydrophila, is representative of a group of β-sheet toxins that must form stable homooligomers in order to be able to insert into biological membranes and generate channels. Electron microscopy and image analysis of two-dimensional membrane crystals had previously revealed a structure with 7-fold symmetry et al. (1992) EMBO J. 11, 2457–2463]. However, this unusual et al. (1992) EMBO J. 11, 2457–2463]. However, this unusual molecularity of the channel remained to be confirmed by an independent method since low-resolution electron crystallography had led to artefactual data for other pore-forming toxins. In this study, matrix-assisted laser desorption/ionization time-of-flight mass s...
Aerolysin is the founding member of a superfamily of β-pore–forming toxins whose pore structure is u...
The channel-forming protein aerolysin is secreted as a protoxin which can be activated by proteolyti...
The alpha helical CytolysinA family of pore forming toxins (α-PFT) contains single, two, and three c...
AbstractAerolysin, a virulence factor secreted by Aeromonas hydrophila, is representative of a group...
Aerolysin is a bacterial pore-forming toxin that is secreted as an inactive precursor, which is then...
Owing to their pathogenical role and unique ability to exist both as soluble proteins and transmembr...
Aerolysin is the founding member of a superfamily of β-pore-forming toxins whose pore structure is u...
Abstract: Pore-forming toxins (PFTs) represent the largest known group of bacterial protein toxins t...
AbstractAerolysin is a channel-forming toxin responsible for the pathogenicity of Aeromonas hydrophi...
Aerolysin is one of a large group of bacterial proteins that can kill target cells by forming discre...
International audiencePore-forming toxins (PFTs) represent the largest known group of bacterial prot...
The alpha helical CytolysinA family of pore forming toxins (α-PFT) contains single, two, and three c...
The invertebrate cytolysin lysenin is a member of the aerolysin family of pore-forming toxins that i...
The pore-forming toxin aerolysin is secreted by Aero-monas hydrophila as an inactive precursor. Base...
The invertebrate cytolysin lysenin is a member of the aerolysin family of pore-forming toxins that i...
Aerolysin is the founding member of a superfamily of β-pore–forming toxins whose pore structure is u...
The channel-forming protein aerolysin is secreted as a protoxin which can be activated by proteolyti...
The alpha helical CytolysinA family of pore forming toxins (α-PFT) contains single, two, and three c...
AbstractAerolysin, a virulence factor secreted by Aeromonas hydrophila, is representative of a group...
Aerolysin is a bacterial pore-forming toxin that is secreted as an inactive precursor, which is then...
Owing to their pathogenical role and unique ability to exist both as soluble proteins and transmembr...
Aerolysin is the founding member of a superfamily of β-pore-forming toxins whose pore structure is u...
Abstract: Pore-forming toxins (PFTs) represent the largest known group of bacterial protein toxins t...
AbstractAerolysin is a channel-forming toxin responsible for the pathogenicity of Aeromonas hydrophi...
Aerolysin is one of a large group of bacterial proteins that can kill target cells by forming discre...
International audiencePore-forming toxins (PFTs) represent the largest known group of bacterial prot...
The alpha helical CytolysinA family of pore forming toxins (α-PFT) contains single, two, and three c...
The invertebrate cytolysin lysenin is a member of the aerolysin family of pore-forming toxins that i...
The pore-forming toxin aerolysin is secreted by Aero-monas hydrophila as an inactive precursor. Base...
The invertebrate cytolysin lysenin is a member of the aerolysin family of pore-forming toxins that i...
Aerolysin is the founding member of a superfamily of β-pore–forming toxins whose pore structure is u...
The channel-forming protein aerolysin is secreted as a protoxin which can be activated by proteolyti...
The alpha helical CytolysinA family of pore forming toxins (α-PFT) contains single, two, and three c...