Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them for degradation. Two recent reports reveal that phagophores, the autophagosome precursors, are surrounded by and connected to rough endoplasmic reticulum (ER) membranes. These results shed light on how membranes may be supplied and reorganized for autophagosomal biogenesis
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial m...
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic components, ...
Autophagic protein degradation is mediated by autophagosomes that fuse with lysosomes, where their c...
Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them...
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and pr...
Autophagy is a conserved catabolic process critical for cell homeostasis with broad implications for...
Although it is well appreciated that autophagy begins with phagophore formation and expansion throug...
Autophagosomes form in eukaryotic cells in response to starvation or to other stress conditions brou...
Autophagy is a catabolic intracellular process highly conserved among eukaryotes. During this proces...
AbstractMacro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplas...
Autophagosome biogenesis occurs in the transient subdomains of the endoplasmic reticulum that are ca...
Autophagosomes are double-membrane sequestering vesicles that are the hallmark of the intracellular ...
textabstractAutophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cyt...
<p>A. The process of autophagy. Cytoplasmic material (here a bacterium) is targeted by an isolation ...
The membrane origins of autophagosomes have been a key unresolved question in the field. The earlies...
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial m...
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic components, ...
Autophagic protein degradation is mediated by autophagosomes that fuse with lysosomes, where their c...
Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them...
Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and pr...
Autophagy is a conserved catabolic process critical for cell homeostasis with broad implications for...
Although it is well appreciated that autophagy begins with phagophore formation and expansion throug...
Autophagosomes form in eukaryotic cells in response to starvation or to other stress conditions brou...
Autophagy is a catabolic intracellular process highly conserved among eukaryotes. During this proces...
AbstractMacro-autophagy (autophagy) is a conserved catabolic pathway for the degradation of cytoplas...
Autophagosome biogenesis occurs in the transient subdomains of the endoplasmic reticulum that are ca...
Autophagosomes are double-membrane sequestering vesicles that are the hallmark of the intracellular ...
textabstractAutophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cyt...
<p>A. The process of autophagy. Cytoplasmic material (here a bacterium) is targeted by an isolation ...
The membrane origins of autophagosomes have been a key unresolved question in the field. The earlies...
The de novo generation of double-membrane autophagosomes is the hallmark of autophagy. The initial m...
Macroautophagy, or simply autophagy, is a degradative pathway that delivers cytoplasmic components, ...
Autophagic protein degradation is mediated by autophagosomes that fuse with lysosomes, where their c...
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