The relationship between pre-sleep arousal and spontaneous arousals from sleep in subjects referred for diagnostic polysomnograms

AbstractBackgroundTo explore the relationship between pre-sleep arousability and spontaneous arousals from sleep, we conducted a cross-sectional study.MethodsFour hundred and four outpatients with suspected sleep-disordered breathing who had received diagnostic polysomnograms were enrolled. Spontaneous arousals from sleep were identified by electroencephalogram and scored according to the criteria of the American Academy of Sleep Medicine. Pre-sleep arousals were evaluated with the Pre-sleep Arousal Scale.ResultsAfter controlling for confounders, the Cognitive subscale was correlated with spontaneous arousal indices during non-rapid eye movement sleep (b=0.41, p=0.01). Among patients with apnea-hypopnea index