Effects of interval-load versus constant-load training on the BODE index in COPD patients

SummaryThe BODE index is frequently used to assess functional capacity in patients with COPD. The aim of this study was to investigate the effectiveness of interval-load training (ILT) to improve the BODE index in comparison to the commonly implemented constant-load training (CLT).Forty-two patients with COPD [FEV1: (mean±SEM) 42±3% predicted] were randomly allocated to either ILT (n=21) or CLT (n=21). The training program consisted of cycling exercise 3 days/week for 10 weeks. Patients assigned to ILT exercised at a mean intensity of 126±4% of baseline peak work rate (Wpeak) with 30-s work periods alternated with 30-s rest periods for 45min per day, whereas patients allocated to CLT exercised at a mean intensity of 76±5% of baseline Wpeak for 30min per day. The BODE index and its components: body mass index, FEV1, MMRC dyspnea score and the 6-min walk test (6-MWT) as well as cycling Wpeak were assessed before and after both exercise training regimes.Both ILT and CLT significantly (p