Oxysterol binding protein (OSBP) and many of its homologs transfer sterol in vitro, but in vivo, they are not major sterol transporters. In this issue of Structure, Tong and colleagues find that the yeast OSBP homolog, Osh3, binds PI(4)P but not sterol, supporting the view that PI(4)P regulation, not sterol transport, is the key activity for OSBP homologs
International audienceSeveral proteins at endoplasmic reticulum (ER)-Golgi membrane contact sites co...
Human ORP3 belongs to the oxysterol-binding protein (OSBP) family of lipid transfer proteins and is ...
The oxysterol-binding protein-related protein (ORP) family is essential to sterol transfer and stero...
Oxysterol binding protein (OSBP) and many of its homologs transfer sterol in vitro, but in vivo, the...
SummaryThe oxysterol-binding protein (OSBP)-related proteins (ORPs) are conserved from yeast to huma...
Oxysterol binding protein (OSBP) and its homologs have been shown to regulate lipid metabolism and v...
Oxysterol-binding protein (OSBP) and its homologs designated OSBP-related (ORP) or OSBP-like (OSBPL)...
In the budding yeast Saccharomyces cerevisiae, seven OSBP-homologues (Osh) proteins are implicated i...
The yeast genome encodes seven oxysterol binding protein homologs, Osh1p-Osh7p, which have been impl...
Cell polarity is maintained via a balance of exocytosis and endocytosis; the protein machinery that ...
Sterols such as cholesterol in mammals and ergosterol in fungi are essential membrane components and...
Protein families related to OSBP (oxysterol-binding protein) are present in eukaryotes from yeast to...
Cytoplasmic oxysterol-binding protein homologues, designated OSBP-like (OSBPL) or OSBP-related (ORP)...
OSBP (oxysterol-binding protein) homologues, ORPs (OSBPrelated proteins), constitute a 12-member fam...
International audienceLipids are precisely distributed in the eukaryotic cell where they help to def...
International audienceSeveral proteins at endoplasmic reticulum (ER)-Golgi membrane contact sites co...
Human ORP3 belongs to the oxysterol-binding protein (OSBP) family of lipid transfer proteins and is ...
The oxysterol-binding protein-related protein (ORP) family is essential to sterol transfer and stero...
Oxysterol binding protein (OSBP) and many of its homologs transfer sterol in vitro, but in vivo, the...
SummaryThe oxysterol-binding protein (OSBP)-related proteins (ORPs) are conserved from yeast to huma...
Oxysterol binding protein (OSBP) and its homologs have been shown to regulate lipid metabolism and v...
Oxysterol-binding protein (OSBP) and its homologs designated OSBP-related (ORP) or OSBP-like (OSBPL)...
In the budding yeast Saccharomyces cerevisiae, seven OSBP-homologues (Osh) proteins are implicated i...
The yeast genome encodes seven oxysterol binding protein homologs, Osh1p-Osh7p, which have been impl...
Cell polarity is maintained via a balance of exocytosis and endocytosis; the protein machinery that ...
Sterols such as cholesterol in mammals and ergosterol in fungi are essential membrane components and...
Protein families related to OSBP (oxysterol-binding protein) are present in eukaryotes from yeast to...
Cytoplasmic oxysterol-binding protein homologues, designated OSBP-like (OSBPL) or OSBP-related (ORP)...
OSBP (oxysterol-binding protein) homologues, ORPs (OSBPrelated proteins), constitute a 12-member fam...
International audienceLipids are precisely distributed in the eukaryotic cell where they help to def...
International audienceSeveral proteins at endoplasmic reticulum (ER)-Golgi membrane contact sites co...
Human ORP3 belongs to the oxysterol-binding protein (OSBP) family of lipid transfer proteins and is ...
The oxysterol-binding protein-related protein (ORP) family is essential to sterol transfer and stero...
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