Risk of cardiovascular disease in relation to achieved office and ambulatory blood pressure control in treated hypertensive subjects

AbstractObjectiveWe investigated the prognostic impact of 24-h blood pressure control in treated hypertensive subjects.BackgroundThere is growing evidence that ambulatory blood pressure improves risk stratification in untreated subjects with essential hypertension. Surprisingly, little is known on the prognostic value of this procedure in treated subjects.MethodsDiagnostic procedures including 24-h noninvasive ambulatory blood pressure monitoring were undertaken in 790 subjects with essential hypertension (mean age 48 years) before therapy and after an average follow-up of 3.7 years (2,891 patient-years).ResultsAt the follow-up visit, 26.6% of subjects achieved adequate office blood pressure control (<140/90 mm Hg), and 37.3% of subjects achieved adequate ambulatory blood pressure control (daytime blood pressure