Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, leading to autoimmunity. Deane et al. (2007) show that Tlr7 gene dosage is directly related to the risk of lupus in a mouse model
SummarySystemic lupus erythematosus (SLE) is characterized by the production of autoantibodies that ...
Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, lea...
Although circumstantial evidence supports enhanced Toll-like receptor 7 (TLR7) signalling as a mecha...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
The global increase in autoimmunity, together with the emerging autoimmune-related side effects of c...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
The immune system is a well-honed machinery that is able to walk the fine line of balance between pa...
Accumulating evidence supports the idea that TLR7 and TLR9 play pathogenic and protective roles, res...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
International audienceSystemic lupus erythematosus (SLE) is a complex autoimmune disease with divers...
International audienceSystemic lupus erythematosus (SLE) is a complex autoimmune disease with divers...
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by B cell hyperactivity l...
SummarySystemic lupus erythematosus (SLE) is characterized by the production of autoantibodies that ...
Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, lea...
Although circumstantial evidence supports enhanced Toll-like receptor 7 (TLR7) signalling as a mecha...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
The global increase in autoimmunity, together with the emerging autoimmune-related side effects of c...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
The immune system is a well-honed machinery that is able to walk the fine line of balance between pa...
Accumulating evidence supports the idea that TLR7 and TLR9 play pathogenic and protective roles, res...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
International audienceSystemic lupus erythematosus (SLE) is a complex autoimmune disease with divers...
International audienceSystemic lupus erythematosus (SLE) is a complex autoimmune disease with divers...
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by B cell hyperactivity l...
SummarySystemic lupus erythematosus (SLE) is characterized by the production of autoantibodies that ...
Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, lea...
Although circumstantial evidence supports enhanced Toll-like receptor 7 (TLR7) signalling as a mecha...