Trimethylation of histone H3 on Lys36 (H3K36me3) by SETD2 is linked to actively transcribed regions. Li et al. identify a novel role for H3K36me3 that facilitates DNA mismatch repair (MMR) in cells by targeting the MMR machinery to chromatin during the cell cycle, thereby explaining certain cases of MMR-defective cancers
The DNA mismatch repair (MMR) system maintains genome integrity by correcting replication errors. MM...
DNA mismatch repair (MMR) is a highly conserved cellular process that functions in the maintenance o...
The DNA mismatch repair (MMR) system is highly conserved and vital for preserving genomic integrity....
Trimethylation of histone H3 on Lys36 (H3K36me3) by SETD2 is linked to actively transcribed regions....
SummaryDNA mismatch repair (MMR) ensures replication fidelity by correcting mismatches generated dur...
SummaryModulating chromatin through histone methylation orchestrates numerous cellular processes. SE...
Modulating chromatin through histone methylation orchestrates numerous cellular processes. SETD2-dep...
Histone modifications play diverse and essential roles in the maintenance of genome integrity, as ev...
The DNA mismatch repair (MMR) pathway, a crucial post-replicative repair pathway, is essential to th...
DNA is wrapped around proteins called histones, whose modification regulates numerous cellular proce...
Comprehensive sequencing of human cancers has identified frequent mutations in genes encoding chroma...
Although the molecular genetics regulating DNA replication onset have been studied in great detail, ...
Chromatin structure is a major barrier to gene transcription that must be disrupted and re-set durin...
Histone modifications are major determinants of DNA double-strand break (DSB) response and repair. H...
Histone modifications affect many cellular processes including DNA damage repair. This thesis focuss...
The DNA mismatch repair (MMR) system maintains genome integrity by correcting replication errors. MM...
DNA mismatch repair (MMR) is a highly conserved cellular process that functions in the maintenance o...
The DNA mismatch repair (MMR) system is highly conserved and vital for preserving genomic integrity....
Trimethylation of histone H3 on Lys36 (H3K36me3) by SETD2 is linked to actively transcribed regions....
SummaryDNA mismatch repair (MMR) ensures replication fidelity by correcting mismatches generated dur...
SummaryModulating chromatin through histone methylation orchestrates numerous cellular processes. SE...
Modulating chromatin through histone methylation orchestrates numerous cellular processes. SETD2-dep...
Histone modifications play diverse and essential roles in the maintenance of genome integrity, as ev...
The DNA mismatch repair (MMR) pathway, a crucial post-replicative repair pathway, is essential to th...
DNA is wrapped around proteins called histones, whose modification regulates numerous cellular proce...
Comprehensive sequencing of human cancers has identified frequent mutations in genes encoding chroma...
Although the molecular genetics regulating DNA replication onset have been studied in great detail, ...
Chromatin structure is a major barrier to gene transcription that must be disrupted and re-set durin...
Histone modifications are major determinants of DNA double-strand break (DSB) response and repair. H...
Histone modifications affect many cellular processes including DNA damage repair. This thesis focuss...
The DNA mismatch repair (MMR) system maintains genome integrity by correcting replication errors. MM...
DNA mismatch repair (MMR) is a highly conserved cellular process that functions in the maintenance o...
The DNA mismatch repair (MMR) system is highly conserved and vital for preserving genomic integrity....