A new study by Shimono et al. (2009) demonstrates that certain microRNAs that regulate the self-renewal factor BMI1 are downregulated in purified populations of normal mammary epithelial stem cells and breast tumor-initiating cells. These findings have important implications for the regulation of self-renewal and differentiation by microRNAs and suggest new ways of targeting cancer stem cells
The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is int...
miRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by regu...
The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic fa...
A new study by Shimono et al. (2009) demonstrates that certain microRNAs that regulate the self-rene...
International audiencemiRNAs are essential for self-renewal and differentiation of normal and malign...
SummaryHuman breast tumors contain a breast cancer stem cell (BCSC) population with properties remin...
microRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by r...
Reactivation of the stem cell programme in breast cancer is significantly associated with persistent...
A novel microRNA family as molecular determinant in mammary stem cells MicroRNAs (miRNAs) are an ev...
The ability to self-renew and to differentiate into at least one-cell lineage defines a stem cell. S...
Cancer stem cells (CSCs) are a small part of the heterogeneous tumor cell population possessing self...
Background: The Bmi1 polycomb ring finger oncogene, a transcriptional repressor belonging to the Pol...
This is the published version, also available here: http://www.ijcem.com/1002003A.html.Emerging evid...
International audienceBreast cancer stem cells (bCSCs) have been implicated in tumor progression and...
MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell maintenan...
The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is int...
miRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by regu...
The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic fa...
A new study by Shimono et al. (2009) demonstrates that certain microRNAs that regulate the self-rene...
International audiencemiRNAs are essential for self-renewal and differentiation of normal and malign...
SummaryHuman breast tumors contain a breast cancer stem cell (BCSC) population with properties remin...
microRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by r...
Reactivation of the stem cell programme in breast cancer is significantly associated with persistent...
A novel microRNA family as molecular determinant in mammary stem cells MicroRNAs (miRNAs) are an ev...
The ability to self-renew and to differentiate into at least one-cell lineage defines a stem cell. S...
Cancer stem cells (CSCs) are a small part of the heterogeneous tumor cell population possessing self...
Background: The Bmi1 polycomb ring finger oncogene, a transcriptional repressor belonging to the Pol...
This is the published version, also available here: http://www.ijcem.com/1002003A.html.Emerging evid...
International audienceBreast cancer stem cells (bCSCs) have been implicated in tumor progression and...
MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell maintenan...
The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is int...
miRNAs are essential for self-renewal and differentiation of normal and malignant stem cells by regu...
The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic fa...
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