The rapidly adapting (RA) low-threshold mechanoreceptors respond to movement of the skin and vibration and are critical for the perception of texture and shape. In this issue of Neuron, two papers (Bourane et al. and Luo et al.) demonstrate that early-born Ret+ sensory neurons are RA mechanoreceptors, whose peripheral nerve terminals are associated with Meissner corpuscles, longitudinal lanceolate endings, and Pacinian corpuscles. The studies further show that Ret signaling is essential for the development of these mechanoreceptors
Differences in gene expression and sensory modality indicate that sensory neurons of dorsal root gan...
Rapid adapting type-I (RA-I) receptor is one type of mechanoreceptors in the human skin. They are be...
Ke.y words: human skin- mechanoreceptors- edge sensitivity One type of rapidly adapting (RA) and one...
SummaryIn mammals, the first step in the perception of form and texture is the activation of trigemi...
Somatosensation is critical for interaction with the surrounding environment. Somatosensory stimuli ...
Somatosensation is critical for interaction with the surrounding environment. Somatosensory stimuli ...
SummaryLow-threshold mechanoreceptor neurons (LTMs) of the dorsal root ganglia (DRG) are essential f...
Tactile information is critical for our ability to manipulate objects, recognize textures, and provi...
Tactile information is critical for our ability to manipulate objects, recognize textures, and provi...
© 2015, eLife Sciences Publications Ltd. All Rights Reserved.Neurons develop highly stereotyped rece...
The recent discovery of nociceptive Schwann cells has changed our vision of how mechanotransduction ...
Tactile sensory discrimination is dependent upon an intact system of peripheral mechanoreceptors, th...
peer reviewedCutaneous nerves are either somatic sensory afferents to ganglion neurons or terminal e...
RET can be activated in cis or trans by its co-receptors and ligands in vitro, but the physiological...
Somatosensory low threshold mechanoreceptors (LTMRs) sense innocuous mechanical forces, largely thro...
Differences in gene expression and sensory modality indicate that sensory neurons of dorsal root gan...
Rapid adapting type-I (RA-I) receptor is one type of mechanoreceptors in the human skin. They are be...
Ke.y words: human skin- mechanoreceptors- edge sensitivity One type of rapidly adapting (RA) and one...
SummaryIn mammals, the first step in the perception of form and texture is the activation of trigemi...
Somatosensation is critical for interaction with the surrounding environment. Somatosensory stimuli ...
Somatosensation is critical for interaction with the surrounding environment. Somatosensory stimuli ...
SummaryLow-threshold mechanoreceptor neurons (LTMs) of the dorsal root ganglia (DRG) are essential f...
Tactile information is critical for our ability to manipulate objects, recognize textures, and provi...
Tactile information is critical for our ability to manipulate objects, recognize textures, and provi...
© 2015, eLife Sciences Publications Ltd. All Rights Reserved.Neurons develop highly stereotyped rece...
The recent discovery of nociceptive Schwann cells has changed our vision of how mechanotransduction ...
Tactile sensory discrimination is dependent upon an intact system of peripheral mechanoreceptors, th...
peer reviewedCutaneous nerves are either somatic sensory afferents to ganglion neurons or terminal e...
RET can be activated in cis or trans by its co-receptors and ligands in vitro, but the physiological...
Somatosensory low threshold mechanoreceptors (LTMRs) sense innocuous mechanical forces, largely thro...
Differences in gene expression and sensory modality indicate that sensory neurons of dorsal root gan...
Rapid adapting type-I (RA-I) receptor is one type of mechanoreceptors in the human skin. They are be...
Ke.y words: human skin- mechanoreceptors- edge sensitivity One type of rapidly adapting (RA) and one...