Two or More Levels Anterior Cervical Discectomy and Fusion (ACDF) Using Stand-Alone PEEK Cages Filled With Bone Graft Substitute

Background Data: Anterior cervical discectomy and fusion (ACDF) has become a standard and a highly successful procedure for degenerative cervical disc disease associated with radiculopathy or myelopathy. In addition to graft complication, multilevel cervical discectomy is often combined with plate fixation to maintain the spinal curvature, and increasing the graft fusion rate but this also may carry risk of complications. Study Design: Prospective descriptive clinical case study Purpose: To evaluate the safety and efficacy of standalone PEEK cages filled with bone graft substitute in treatment of multi-level cervical disc disease. Patients and Methods: Ninety one patients underwent multiple levels ACDF for a total of 239 levels. Mean follow-up was 24 months. Clinical outcomes were evaluated using Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI); cervical lordosis and cervical fusion status was assessed on X-ray. Statistical analysis was performed using a dependent t-test using SPSS V.12.0 (P