Jiayu Li,1 Rong Dong,2 Jiali Yu,2 Sun Yi,2 Jingjing Da,2 Fuxun Yu,3 Yan Zha2 1Guizhou University School of Medicine, Guizhou University, 2Department of Nephrology, Guizhou Provincial People’s Hospital, 3Department of Central Laboratory, Guizhou Provincial People’s Hospital, Guiyang, China Objective: To explore the anti-inflammatory mechanism of IGF1R inhibitor in diabetic nephropathy.Methods: C57/BL6 mice were reared with high-fat diet for 8 weeks, then were injected 30 mg/kg streptozotocin intraperitoneally to induce type 2 diabetes. After 8 weeks, the type 2 diabetes nephropathy model was successfully set up the different drugs were administrated to mice with diabetes (insulin 1–2 U/day, benazepril 10 mg/kg per day ...
Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
<div><p>Growth factor receptor-bound protein 10 (Grb10) is an adaptor protein that can negatively re...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Renal hypertrophy and deposition of extracellular matrix proteins are consistent findings in diabeti...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
<div><p>Growth factor receptor-bound protein 10 (Grb10) is an adaptor protein that can negatively re...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Renal hypertrophy and deposition of extracellular matrix proteins are consistent findings in diabeti...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
Diabetic kidney disease (DKD) is characterized by progressive glomerulosclerosis (GS). ROP mice have...
Loss of podocyte is a characteristic pathological change of diabetic nephropathy (DN) which is assoc...
IntroductionDiabetic kidney disease (DKD) has become the leading cause of end-stage renal disease wo...