THE CUT-OFF POINTS OF WAIST CIRCUMFERENCE FOR DETERMINATION OF RISK OF METABOLIC SYNDROME AMONG MALES AND FEMALES IN REPUBLIC OF KHAKASSIA

Background. The aim of this study was to determine the cut-off points of waist circumference for identification of metabolic syndrome among populations by the Republic of Khakassia. Materials and methods. 300 patients with metabolic syndrome (aged 50 (42–54) years) were investigated. The control group was of 100 healthy donors (43 (36–47) years). All participants were presented by 2 groups – populations of Khakas and Caucasian has been lived in the Republic of Khakassia. The patients who had components of metabolic syndrome by recommendation JIS (2009) were included to research. In the study were evaluated anthropometric characteristics, blood pressure, cholesterine, cholesterol, high-density and low-density lipoprotein cholesterol, triglycerides and glucose levels. Statistical analysis was performed using the application package «BioStat». Results: Our analysis revealed that cut-off values of waist circumference for identification of metabolic syndrome in females Khakas with metabolic syndrome consist of cut-off values of 74 cm (Se – 98,8%, Sp – 93,75%), area under the curve AUC – 0,99, in females Caucasian - 84 cm (Se – 100%, Sp – 100%), area under the curve AUC – 0,97. Сut-off values of cut-off values of waist circumference in males Khakas with metabolic syndrome consist of 92 cm (Se – 100%, Sp – 100%), area under the curve AUC – 1,0, in males Caucasian – 96 cm (Se – 100%, Sp – 100%), area under the curve AUC – 0,99. Conclusion: thus, from patients with components of metabolic syndrome have been determined cut-off values of waist circumference for identification of metabolic syndrome. The findings showed are ethnic features of pathogenesis of metabolic disorders from males and females in Republic of Khakassia