The overactive bladder (OAB) is a debilitating condition in which patients suffer from urinary urgency, frequency and nocturia with or without urge urinary incontinence. The mainstay of pharmacotherapy for OAB is muscarinic receptor antagonists, which have been shown to be effective treatments for the symptoms of OAB. The mechanism underlying the efficacy of antimuscarinic agents against the symptoms of OAB is not completely understood. This review explores the role of bladder mucosal muscarinic receptors in the signaling pathways that are activated in response to bladder filling. The cholinergic system is seen to be involved in bladder afferent signaling at many levels and as such muscarinic receptor antagonists may affect bladder signalin...
AbstractThe aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-i...
A substantial portion of the current research on lower urinary tract dysfunction is focused on affer...
Purpose: The isolated bladder expresses autonomous activity, which may contribute to the generation ...
1 The effectiveness of antimuscarinic agents in the treatment of the overactive bladder (OAB) syndro...
The overactive bladder (OAB) syndrome is defined as urgency, with or without urgency incontinence, u...
Bladder function during filling and micturition is regulated by peripheral and central nervous and h...
The micturition reflex can be initiated by contraction or distension of detrusor smooth muscle cells...
Well-functioning of the urinary bladder is of utmost importance. Changes in bladder activity can lea...
BACKGROUND: First-line pharmacotherapy for overactive bladder consists of anticholinergics. However,...
This thesis, comprising of clinical studies, basic research as well as review of data, has aimed to ...
Recent studies have described muscarinic receptors on the mucosa and the detrusor of the human urina...
Contemporary, the management of overactive bladder (OAB), a medical condition characterized by urgen...
INTRODUCTION: Licenced oral pharmacotherapies for overactive bladder (OAB) act on muscarinic recept...
Stress incontinence and overactive bladder are disorders with a common symptom, urinary incontinence...
Contemporary, the management of overactive bladder (OAB), a medical condition characterized by urgen...
AbstractThe aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-i...
A substantial portion of the current research on lower urinary tract dysfunction is focused on affer...
Purpose: The isolated bladder expresses autonomous activity, which may contribute to the generation ...
1 The effectiveness of antimuscarinic agents in the treatment of the overactive bladder (OAB) syndro...
The overactive bladder (OAB) syndrome is defined as urgency, with or without urgency incontinence, u...
Bladder function during filling and micturition is regulated by peripheral and central nervous and h...
The micturition reflex can be initiated by contraction or distension of detrusor smooth muscle cells...
Well-functioning of the urinary bladder is of utmost importance. Changes in bladder activity can lea...
BACKGROUND: First-line pharmacotherapy for overactive bladder consists of anticholinergics. However,...
This thesis, comprising of clinical studies, basic research as well as review of data, has aimed to ...
Recent studies have described muscarinic receptors on the mucosa and the detrusor of the human urina...
Contemporary, the management of overactive bladder (OAB), a medical condition characterized by urgen...
INTRODUCTION: Licenced oral pharmacotherapies for overactive bladder (OAB) act on muscarinic recept...
Stress incontinence and overactive bladder are disorders with a common symptom, urinary incontinence...
Contemporary, the management of overactive bladder (OAB), a medical condition characterized by urgen...
AbstractThe aim of this study was to compare the effect of antimuscarinic antagonists on carbachol-i...
A substantial portion of the current research on lower urinary tract dysfunction is focused on affer...
Purpose: The isolated bladder expresses autonomous activity, which may contribute to the generation ...