Presently, control of body weight is assumed to exist, but there is no consensus framework of body weight homeostasis. Three different models have been proposed, with a “set point” suggesting (i) a more or less tight and (ii) symmetric or asymmetric biological control of body weight resulting from feedback loops from peripheral organs and tissues (e.g. leptin secreted from adipose tissue) to a central control system within the hypothalamus. Alternatively, a “settling point” rather than a set point reflects metabolic adaptations to energy imbalance without any need for feedback control. Finally, the “dual intervention point” model combines both paradigms with two set points and a settling point between them. In humans, observational studies ...
Dupuytren’s disease is a common fibrotic condition of the hand affecting 4% of the population and ca...
During the past decade, it became clear that the electric field elicited by non-invasive brain stimu...
Background: Exercise may activate a brown adipose-like phenotype in white adipose tissue. The aim of...
Constipation, a condition characterized by heterogeneous symptoms, is common in Western society. It ...
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enabl...
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enabl...
Contextual functional interpretation of -omics data derived from clinical samples is a classical and...
Intensive care unit–acquired weakness (ICU-AW) is the most common neuromuscular impairment in critic...
There has been substantial progress in the management of patients with osteoporosis and the preventi...
SUMMARY Understanding insulin-like growth factor-1 (IGF1) biology is of particular importance becaus...
Microbial adaptation to extreme conditions takes many forms, including specialized metabolism which ...
This review highlights advances made in recent years in the diagnosis and management of acute pancre...
Background: No studies have addressed the fit but fat paradigm using accelerometry data. Aim: The ...
A great number of food matrices have been recognized as susceptible to mycotoxin contamination. The ...
A pressing goal in global development and other sectors is often to understand what drives people’s ...
Dupuytren’s disease is a common fibrotic condition of the hand affecting 4% of the population and ca...
During the past decade, it became clear that the electric field elicited by non-invasive brain stimu...
Background: Exercise may activate a brown adipose-like phenotype in white adipose tissue. The aim of...
Constipation, a condition characterized by heterogeneous symptoms, is common in Western society. It ...
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enabl...
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when activated, enabl...
Contextual functional interpretation of -omics data derived from clinical samples is a classical and...
Intensive care unit–acquired weakness (ICU-AW) is the most common neuromuscular impairment in critic...
There has been substantial progress in the management of patients with osteoporosis and the preventi...
SUMMARY Understanding insulin-like growth factor-1 (IGF1) biology is of particular importance becaus...
Microbial adaptation to extreme conditions takes many forms, including specialized metabolism which ...
This review highlights advances made in recent years in the diagnosis and management of acute pancre...
Background: No studies have addressed the fit but fat paradigm using accelerometry data. Aim: The ...
A great number of food matrices have been recognized as susceptible to mycotoxin contamination. The ...
A pressing goal in global development and other sectors is often to understand what drives people’s ...
Dupuytren’s disease is a common fibrotic condition of the hand affecting 4% of the population and ca...
During the past decade, it became clear that the electric field elicited by non-invasive brain stimu...
Background: Exercise may activate a brown adipose-like phenotype in white adipose tissue. The aim of...