Salmonella pathogenesis relies upon the delivery of over thirty specialized effector proteins into the host cell via two distinct type III secretion systems. These effectors act in concert to subvert the host cell cytoskeleton, signal transduction pathways, membrane trafficking and proinflammatory responses. This allows Salmonella to invade non-phagocytic epithelial cells, establish and maintain an intracellular replicative niche and, in some cases, disseminate to cause systemic diseases. This review focuses on the action of the effectors on their host cell targets during each stage of Salmonella infection
International audienceSalmonella-infected cells are characterized by the presence of intra-cellular ...
International audienceSalmonella is a facultative intracellular bacterium found within a variety of ...
SummaryGram-negative pathogenic bacteria such as Salmonella utilize the type III secretion system to...
Salmonella pathogenesis relies upon the delivery of over thirty specialised effector proteins into t...
Salmonella can be categorized into many serotypes, which are specific to known hosts or broadhosts. ...
Salmonella species are Gram-negative intracellular bacterial pathogens that infect a broad range of ...
The success of Salmonella Typhimurium as a pathogen relies on its ability to invade and survive with...
Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virul...
Salmonella Typhimurium has evolved a complex functional interface with its host cell largely determi...
Salmonella causes disease in humans and animals ranging from mild self-limiting gastroenteritis to p...
The pathogenesis of Salmonella Typhimurium depends on the bacterium's ability to survive and replica...
Mechanical cell fractionation and immunofluorescence microscopy were applied to systematically inves...
Bacteria of the genus Salmonella are one of the most important human pathogens. Salmonella expresses...
<div><p><i>Salmonella</i> Typhimurium has evolved a complex functional interface with its host cell ...
<p>(a) The intracellular life of <i>Salmonella</i>. Invasion of phagocytic and non-phagocytic cells....
International audienceSalmonella-infected cells are characterized by the presence of intra-cellular ...
International audienceSalmonella is a facultative intracellular bacterium found within a variety of ...
SummaryGram-negative pathogenic bacteria such as Salmonella utilize the type III secretion system to...
Salmonella pathogenesis relies upon the delivery of over thirty specialised effector proteins into t...
Salmonella can be categorized into many serotypes, which are specific to known hosts or broadhosts. ...
Salmonella species are Gram-negative intracellular bacterial pathogens that infect a broad range of ...
The success of Salmonella Typhimurium as a pathogen relies on its ability to invade and survive with...
Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virul...
Salmonella Typhimurium has evolved a complex functional interface with its host cell largely determi...
Salmonella causes disease in humans and animals ranging from mild self-limiting gastroenteritis to p...
The pathogenesis of Salmonella Typhimurium depends on the bacterium's ability to survive and replica...
Mechanical cell fractionation and immunofluorescence microscopy were applied to systematically inves...
Bacteria of the genus Salmonella are one of the most important human pathogens. Salmonella expresses...
<div><p><i>Salmonella</i> Typhimurium has evolved a complex functional interface with its host cell ...
<p>(a) The intracellular life of <i>Salmonella</i>. Invasion of phagocytic and non-phagocytic cells....
International audienceSalmonella-infected cells are characterized by the presence of intra-cellular ...
International audienceSalmonella is a facultative intracellular bacterium found within a variety of ...
SummaryGram-negative pathogenic bacteria such as Salmonella utilize the type III secretion system to...