Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising
Previous work in this laboratory demonstrated that a series of benzoic acid analogs, with only minor...
Blood coagulation factors, factor XII (FXII), plasma kallikrein (PK), factor XI (FXI), and high-mole...
The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu...
Biological activity of first synthesized 8 xantine derivatives has been studied. Differences in impa...
The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previou...
Two series of ()-2-phenyl-1-(quinolizidin-1\u3b1-yl)benzimidazoles, 12A\u201326A, and ()-2-phenyl-1-...
Introduction: Cardiovascular diseases are currently the leading cause of global disability and morta...
A series of N1-substituted-4-alkoxybenzamidines was synthesized and tested in vitro for their inhibi...
The present study was aimed at discovering novel biologically active compounds based on the skeleton...
Aim: In present study, the anti-inflammatory activities of a new series of benzimidazole derivatives...
Background: A new indole derivative with the lab code-number SS-68 demonstrates a significant antiar...
According to the current understanding, the hyperactivation of platelets may lead to increased intra...
In the present study, a series of 1,3,4-oxadiazole derivatives (4a-4k) derived from benzimidazole we...
A series of omega-aminoalkoxylxanthones was synthesized and tested in vitro for their ability to inh...
Cardiovascular diseases are one of the major causes of mortality in the western world. As platelet d...
Previous work in this laboratory demonstrated that a series of benzoic acid analogs, with only minor...
Blood coagulation factors, factor XII (FXII), plasma kallikrein (PK), factor XI (FXI), and high-mole...
The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu...
Biological activity of first synthesized 8 xantine derivatives has been studied. Differences in impa...
The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previou...
Two series of ()-2-phenyl-1-(quinolizidin-1\u3b1-yl)benzimidazoles, 12A\u201326A, and ()-2-phenyl-1-...
Introduction: Cardiovascular diseases are currently the leading cause of global disability and morta...
A series of N1-substituted-4-alkoxybenzamidines was synthesized and tested in vitro for their inhibi...
The present study was aimed at discovering novel biologically active compounds based on the skeleton...
Aim: In present study, the anti-inflammatory activities of a new series of benzimidazole derivatives...
Background: A new indole derivative with the lab code-number SS-68 demonstrates a significant antiar...
According to the current understanding, the hyperactivation of platelets may lead to increased intra...
In the present study, a series of 1,3,4-oxadiazole derivatives (4a-4k) derived from benzimidazole we...
A series of omega-aminoalkoxylxanthones was synthesized and tested in vitro for their ability to inh...
Cardiovascular diseases are one of the major causes of mortality in the western world. As platelet d...
Previous work in this laboratory demonstrated that a series of benzoic acid analogs, with only minor...
Blood coagulation factors, factor XII (FXII), plasma kallikrein (PK), factor XI (FXI), and high-mole...
The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu...