Patterns of ischemic injury on brain images in neonatal group B Streptococcal meningitis
- Seo Yeol Choi
- Jong-Wan Kim
- Ji Won Ko
- Young Seok Lee
- Young Pyo Chang
DOIAbstract
Purpose This study investigated patterns of ischemic injury observed in brain images from patients with neonatal group B Streptococcal (GBS) meningitis. Methods Clinical findings and brain images from eight term or near-term newborn infants with GBS meningitis were reviewed. Results GBS meningitis was confirmed in all 8 infants via cerebrospinal fluid (CSF) analysis, and patients tested positive for GBS in both blood and CSF cultures. Six infants (75.0%) showed early onset manifestation of the disease (<7 days); the remaining 2 (25.0%) showed late onset manifestation. In 6 infants (75%), cranial ultrasonography showed focal or diffuse echogenicity, suggesting hypoxic-ischemic injury in the basal ganglia, cerebral hemispheres, and periventri...
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