Prediction of the risk of severe pre-eclampsia in multiple pregnancies and ways of its prevention

Based on the study of indicators of oxidative and antioxidative activity of blood, acute phase protein - lactoferrin, placental growth factor (P1GF)) in the first trimester of pregnancy 6-10 weeks in serum of 226 pregnant women with preeclampsia and multiple pregnancy is developed and implemented a complex of therapeutic and diagnostic procedures, which helped to reduce the risk of severe preeclampsia in 2 times, massive bleeding in 1.2 times and to improve perinatal outcomes due to prolongation of pregnancy ( r = 0,78, p < 0,01)