In order to cover the complexity of coding and extend the generality on the road vehicle-bridge iteration, a process to solve vehicle-bridge interaction considering varied vehicle speed based on a convenient combination of Matlab Simulink and ANSYS is presented. In this way, the road vehicle is modeled in state space and the corresponding motion equations are solved using Simulink. The finite element model for the bridge is established and solved using ANSYS. The so-called inter-history iteration method is adopted to realize the interaction between the vehicle model and the bridge model. Different from typical method of road vehicle-bridge interaction in the vertical direction, a detailed longitudinal force model is set up to take into acco...