The effect of Iron and vitamin D supplementation on the severity of premenstrual syndrome symptoms through High school Female Students in the City of Birjand in 2015- 2016

Background and Aim: Premenstrual syndrome is one of the most common disorders of reproductive age, which has significant effects on women's economic, social and professional status. The aim of this study was to determine the effect of  Iron and vitamin D supplementation on the severity of premenstrual syndrome symptoms through High school Students in the City of Birjand in 2015- 2016. Materials and Methods: This quasi-experimental study was performed on 149 students in the grade of Junior high school and senior high school which were selected by random sampling. The participants completed the standard questionnaire for the screening of premenstrual symptoms in order to measure the mood, physical symptoms and effects of these symptoms in the three stages before and after 16 weeks of iron and 9 months of vitamin D supplementation. Data were analyzed by SPSS software (version 16) using Chi-square test, repeat ANOVA, one-way ANOVA and Friedman non-parametric test were analyzed at a significant level less than 0.05. Results: There were 56 students (37.6%) in the PMS group, 19 (12.8%) in the PMDD group and 74 (49.7%) in the non-affected group. The comparison of scores in three study periods showed that the severity of affective symptoms (p=0.005) and effects of the symptoms (p=0.015) in the PMDD group, and only the effects of symptoms (p=0.011) in the PMS group, were reduced, But there was no change in the scores of somatic symptoms in these two groups. In non-affected group, the scores of these three areas showed a significant increase. Conclusion: The Iron and vitamin D supplementation may reduce symptoms of premenstrual syndrome. Further studies are recommended in this area