(R)-acetoin is a four-carbon platform compound used as the precursor for synthesizing novel optically active materials. Ethylene glycol (EG) is a large-volume two-carbon commodity chemical used as the anti-freezing agent and building-block molecule for various polymers. Currently established microbial fermentation processes for converting monosaccharides to either (R)-acetoin or EG are plagued by the formation of undesirable by-products. We show here that a cell-free bioreaction scheme can generate enantiomerically pure acetoin and EG as co-products from biomass-derived D-xylose. The seven-step, ATP-free system included in situ cofactor regeneration and recruited enzymes from Escherichia coli W3110, Bacillus subtilis shaijiu 32 and Caulobac...
AbstractAcetogenic anaerobic bacteria are defined as organisms employing the Wood–Ljungdahl pathway ...
The canonical glycolysis pathway is responsible for converting glucose into 2 molecules of acetyl-co...
Acetoin (3-hydroxy-2-butanone), an extensively-used food spice and bio-based platform chemical, is u...
Metabolic engineering efforts have led to the development of bioprocesses implemented at an industri...
Background: Ethylene glycol (EG) is a bulk chemical that is mainly used as an anti-freezing agent an...
Glucose, xylose and arabinose are the three most abundant monosaccharide found in lignocellulosic bi...
Pyruvate is a hub of various endogenous metabolic pathways, including glycolysis, TCA cycle, amino a...
Abstract Background Acetoin (3-hydroxy-2-butanone), the precursor of biofuel 2,3-butanediol, is an i...
Abstract Background The shortage of food based feedstocks has been one of the stumbling blocks in in...
The functional reconstruction of acetoin and meso-2,3-butanediol (meso-2,3-BD) biosynthetic pathway...
International audienceBackground: Ethylene glycol (EG) is a bulk chemical that is mainly used as an ...
BACKGROUND: Most low molecular diols are highly water-soluble, hygroscopic, and reactive with many o...
Acetoin (3-hydroxy-2-butanone) is an important bio-based platform chemical with wide applications. I...
Biorefinery to produce value-added biochemicals offers a promising alternative to meet our sustainab...
Ethanol is a widely available carbon compound that can be increasingly produced with a net negative ...
AbstractAcetogenic anaerobic bacteria are defined as organisms employing the Wood–Ljungdahl pathway ...
The canonical glycolysis pathway is responsible for converting glucose into 2 molecules of acetyl-co...
Acetoin (3-hydroxy-2-butanone), an extensively-used food spice and bio-based platform chemical, is u...
Metabolic engineering efforts have led to the development of bioprocesses implemented at an industri...
Background: Ethylene glycol (EG) is a bulk chemical that is mainly used as an anti-freezing agent an...
Glucose, xylose and arabinose are the three most abundant monosaccharide found in lignocellulosic bi...
Pyruvate is a hub of various endogenous metabolic pathways, including glycolysis, TCA cycle, amino a...
Abstract Background Acetoin (3-hydroxy-2-butanone), the precursor of biofuel 2,3-butanediol, is an i...
Abstract Background The shortage of food based feedstocks has been one of the stumbling blocks in in...
The functional reconstruction of acetoin and meso-2,3-butanediol (meso-2,3-BD) biosynthetic pathway...
International audienceBackground: Ethylene glycol (EG) is a bulk chemical that is mainly used as an ...
BACKGROUND: Most low molecular diols are highly water-soluble, hygroscopic, and reactive with many o...
Acetoin (3-hydroxy-2-butanone) is an important bio-based platform chemical with wide applications. I...
Biorefinery to produce value-added biochemicals offers a promising alternative to meet our sustainab...
Ethanol is a widely available carbon compound that can be increasingly produced with a net negative ...
AbstractAcetogenic anaerobic bacteria are defined as organisms employing the Wood–Ljungdahl pathway ...
The canonical glycolysis pathway is responsible for converting glucose into 2 molecules of acetyl-co...
Acetoin (3-hydroxy-2-butanone), an extensively-used food spice and bio-based platform chemical, is u...