Add to ORKGSynthesis of a series of new cannabinoid receptor ligands obtained from the conjugation of 1,2-dihydro-2-oxo-pyridine-3-carboxamides portion of A or B with the anomeric or C(6) position of monosaccharide units (D-Gluco, D-galacto and GlcNAc). The new compounds were designed with the aim to increase hydrophilicity and activity of multitarget compounds A and of CB2R positive modulators B. The new compounds will be tested for their biocompatibility and biologically properties
CB2 receptor selective ligands are becoming increasingly attractive drugs due to the potential role ...
Cannabinoid receptors (CB1R and CB2R) and endocannabinoid ligands (anandamide and 2-arachidonoylglyc...
Recent data indicated that the CB,, cannabinoid receptor constitutes an attractive drug target due t...
Synthesis of a series of new cannabinoid receptor ligands obtained from the conjugation of 1,2-dihyd...
Several preclinical evidence indicate that the modulation of the endocannabinoid system (ECS) repres...
Several preclinical evidence indicate that the modulation of the endocannabinoid system (ECS) repres...
Cannabinoid receptors and endocannabinoid ligands, together with the enzymes implicated in endocanna...
The Endocannabinoid System (ECS) is a complex lipid signaling system composed by at least two cannab...
The endocannabinoid system (ECS) represents one of the major neuromodulatory systems involved in dif...
The endocannabinoid system (ECS) represents one of the major neuromodulatory systems involved in dif...
Progettazion e sintesi di composti monociclici con attività verso i recettori dei cannabinoidi
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
The endocannabinoid system (ECS) is a neuromodulatory system, able to modulate different physiologic...
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
CB2 receptor selective ligands are becoming increasingly attractive drugs due to the potential role ...
Cannabinoid receptors (CB1R and CB2R) and endocannabinoid ligands (anandamide and 2-arachidonoylglyc...
Recent data indicated that the CB,, cannabinoid receptor constitutes an attractive drug target due t...
Synthesis of a series of new cannabinoid receptor ligands obtained from the conjugation of 1,2-dihyd...
Several preclinical evidence indicate that the modulation of the endocannabinoid system (ECS) repres...
Several preclinical evidence indicate that the modulation of the endocannabinoid system (ECS) repres...
Cannabinoid receptors and endocannabinoid ligands, together with the enzymes implicated in endocanna...
The Endocannabinoid System (ECS) is a complex lipid signaling system composed by at least two cannab...
The endocannabinoid system (ECS) represents one of the major neuromodulatory systems involved in dif...
The endocannabinoid system (ECS) represents one of the major neuromodulatory systems involved in dif...
Progettazion e sintesi di composti monociclici con attività verso i recettori dei cannabinoidi
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
The endocannabinoid system (ECS) is a neuromodulatory system, able to modulate different physiologic...
A series of N-alkyl 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides were synthesized as new lig...
CB2 receptor selective ligands are becoming increasingly attractive drugs due to the potential role ...
Cannabinoid receptors (CB1R and CB2R) and endocannabinoid ligands (anandamide and 2-arachidonoylglyc...
Recent data indicated that the CB,, cannabinoid receptor constitutes an attractive drug target due t...