Add to ORKGMucoviscidosis/ cystic fibrosis represents a potentially fatal disease, characterized by heterogeneous clinical features, mainly pulmonary, digestive, cardiac, but other systems may be involved. In recent years, there were constant concerns to identify the pathogenic disease mechanism. The molecular genetics techniques revealedin 1989 that cystic fibrosis comes from the defects of a single gene that decodes the cystic fibrosis transmembranar receptor (CFTR), a chloride channel that is distributed on a large scale in the membrane surfaces. CFTR is expressedby the airways epithelium, paranasal sinuses, pancreas, bowel, billiary tract, vasdeferens and sweat glands epithelia.Abnormalitiesin CFTR functioncause pulmonary infections and bronchecta...
Cystic fibrosis (CF) or mucoviscidosis is the most common inherited disease of white race. Is a hete...
Cystic fibrosis (CF) is the most common severe recessive genetic disorder in the Caucasian populatio...
Cystic fibrosis is an autosomal recessive genetic disorder, characterized by mutation in the cystic ...
Cystic fibrosis (CF) is a reversed autosomal genetic disease that originates from some white or cauc...
textabstractCystic fibrosis (CF) is the most common single gene disorder in The Netherlands and occu...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis (CF) is an autosomal recessive genetic disease that affects 1 out of every 2500 indi...
be involved. Pulmonary disease is the result of obstruction of airways by inspissated mucous, which ...
Cystic fibrosis (CF) is a multisystemic autosomal recessive disease caused by a defect in the expre...
Cystic Fibrosis (CF) is a genetic disorder which results in abnormal Cystic Fibrosis Transmembrane R...
Cystic fibrosis (CF) is an autosomal recessive disorder due to mutations in the Cystic Fibrosis Tran...
Our insight into cystic fibrosis (CF) and diseases associated with CF gene mutations has changed. Cy...
Our current understanding of cystic fibrosis (CF) has revealed that the biophysical properties of mu...
Cystic Fibrosis (CF) is a lethal disease affecting children, adolescents and mature adults. However,...
Cystic fibrosis (CF) is caused by mutations in autosomal recessive genes that code for proteins cyst...
Cystic fibrosis (CF) or mucoviscidosis is the most common inherited disease of white race. Is a hete...
Cystic fibrosis (CF) is the most common severe recessive genetic disorder in the Caucasian populatio...
Cystic fibrosis is an autosomal recessive genetic disorder, characterized by mutation in the cystic ...
Cystic fibrosis (CF) is a reversed autosomal genetic disease that originates from some white or cauc...
textabstractCystic fibrosis (CF) is the most common single gene disorder in The Netherlands and occu...
Cystic fibrosis was first recognized as a new disease in 1938 when autopsies of children who died fr...
Cystic fibrosis (CF) is an autosomal recessive genetic disease that affects 1 out of every 2500 indi...
be involved. Pulmonary disease is the result of obstruction of airways by inspissated mucous, which ...
Cystic fibrosis (CF) is a multisystemic autosomal recessive disease caused by a defect in the expre...
Cystic Fibrosis (CF) is a genetic disorder which results in abnormal Cystic Fibrosis Transmembrane R...
Cystic fibrosis (CF) is an autosomal recessive disorder due to mutations in the Cystic Fibrosis Tran...
Our insight into cystic fibrosis (CF) and diseases associated with CF gene mutations has changed. Cy...
Our current understanding of cystic fibrosis (CF) has revealed that the biophysical properties of mu...
Cystic Fibrosis (CF) is a lethal disease affecting children, adolescents and mature adults. However,...
Cystic fibrosis (CF) is caused by mutations in autosomal recessive genes that code for proteins cyst...
Cystic fibrosis (CF) or mucoviscidosis is the most common inherited disease of white race. Is a hete...
Cystic fibrosis (CF) is the most common severe recessive genetic disorder in the Caucasian populatio...
Cystic fibrosis is an autosomal recessive genetic disorder, characterized by mutation in the cystic ...