Are changes in body-mass-index associated with changes in depressive symptoms? Findings of a population-based longitudinal study among older Germans

Abstract Background The longitudinal relationship between BMI and depressive symptoms is not well understood. Therefore, we aimed at investigating the long-term association between body-mass-index (BMI) and depressive symptoms among older Germans. Methods Data were derived from a population-based longitudinal study of adults aged 40 and above in Germany (German Ageing Survey, DEAS). Four waves (2002–2014) were used. Depressive symptoms was assessed by the Center for Epidemiologic Studies Depression Scale (CES-D). Linear, quadratic and cubic terms were included for self-reported BMI. Fixed effects regressions were used to estimate the predictors of depressive symptoms. Results FE regressions showed a curvilinear effect of BMI on depressive symptoms in the total sample and in women, but not men, with significant gender differences. In sum, the greater the extreme of BMI (either higher or lower), the greater the risk for depressive symptoms in the total sample and in women. Conclusion Our findings indicate that the effect of BMI on depressive symptoms is by no means simple. The current study highlight the importance of comprehensive treatment of depression, which include management of (extreme) weight to manage depressive symptoms