Predicting a patient’s risk of recurrence after the resection of liver metastases from colorectal cancer is critical for evaluating and selecting therapeutic approaches. Clinical and pathologic parameters have shown limited accuracy thus far. Therefore, we combined the clinical status with a genomic approach to stratify relapse-free survival in colorectal cancer liver metastases patients. To identify new molecular and genetic signatures specific to colorectal cancer with liver metastasis (CRCLM) patients, we conducted DNA copy number profiling on a cohort of 21 Taiwanese CRCLM patients using a comparative genomic hybridization (CGH) array. We identified a three-gene signature based on differential copy number alteration between patien...
PURPOSE: The aim of this study was to build a molecular prognostic model based on gene signatures fo...
Background Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led...
Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Metastasis remains the pri...
Background We investigated whether genomic aberrations in primary colorectal cancer (CRC) can identi...
Background: Accurate staging of colorectal cancer (CRC) with clinicopathological parameters is impor...
Abstract Background The exploration of genomic alterations in Chinese colorectal liver metastasis (C...
Abstract Background Colorectal cancer is a highly prevalent and deadly. The most common metastatic s...
Liver metastasis is one of the major causes of death in colorectal cancer (CRC) patients. To underst...
Background Colorectal cancer (CRC) is one of the most common causes of cancer-relate...
This study was designed to identify and validate gene signatures that can predict disease free survi...
The majority of genetic studies of colorectal carcinogenesis have focused on changes found in primar...
<div><p>Chromosomal instability is a well-defined hallmark of tumor aggressiveness and metastatic pr...
Purpose: The aim of this study was to build a molecular prognostic model based on gene signatures fo...
mutations and inflammatory status in CRC, especially with respect to liver metastases.-specific sin...
OBJECTIVE: Metastatic colorectal cancer (CRC) cells have a selective preference for certain target o...
PURPOSE: The aim of this study was to build a molecular prognostic model based on gene signatures fo...
Background Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led...
Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Metastasis remains the pri...
Background We investigated whether genomic aberrations in primary colorectal cancer (CRC) can identi...
Background: Accurate staging of colorectal cancer (CRC) with clinicopathological parameters is impor...
Abstract Background The exploration of genomic alterations in Chinese colorectal liver metastasis (C...
Abstract Background Colorectal cancer is a highly prevalent and deadly. The most common metastatic s...
Liver metastasis is one of the major causes of death in colorectal cancer (CRC) patients. To underst...
Background Colorectal cancer (CRC) is one of the most common causes of cancer-relate...
This study was designed to identify and validate gene signatures that can predict disease free survi...
The majority of genetic studies of colorectal carcinogenesis have focused on changes found in primar...
<div><p>Chromosomal instability is a well-defined hallmark of tumor aggressiveness and metastatic pr...
Purpose: The aim of this study was to build a molecular prognostic model based on gene signatures fo...
mutations and inflammatory status in CRC, especially with respect to liver metastases.-specific sin...
OBJECTIVE: Metastatic colorectal cancer (CRC) cells have a selective preference for certain target o...
PURPOSE: The aim of this study was to build a molecular prognostic model based on gene signatures fo...
Background Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led...
Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Metastasis remains the pri...