Abstract Background Autologous urothelial cells are often obtained via bladder biopsy to generate the bio-engineered urethra or bladder, while urine-derived stem cells (USC) can be obtained by a non-invasive approach. The objective of this study is to develop an optimal strategy for urothelium with permeability barrier properties using human USC which could be used for tissue repair in the urinary tract system. Methods USC were harvested from six healthy adult individuals. To optimize urothelial differentiation, five different differentiation methods were studied. The induced cells were assessed for gene and protein expression markers of urothelial cells via RT-PCR, Western blotting, and immunofluorescent staining. Barrier function and ultr...
Although urothelial progenitor-like cells have been described in the human urinary tract, the existe...
Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue ...
AbstractEngineered functional organs or tissues, created with autologous somatic cells and seeded on...
Human stem cells are promising sources for bladder regeneration. Among several possible sources, plu...
As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium...
The urothelium is a specialized epithelium covering the urinary excretory system. In case of lesions...
In vitro generation of human urothelium from stem cells would be a major advancement in the regenera...
The objective of this study was to generate bacterial cellulose (BC) scaffolds seeded with human uri...
Abstract: Human stem cells are promising sources for bladder regeneration. Among several possible so...
<div><p>Although urothelial progenitor-like cells have been described in the human urinary tract, th...
Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue ...
In order to reconstruct injured urinary tract tissues, biodegradable scaffolds with autologous seede...
Abstract BACKGROUND: Urethral reconstruction is one of the great surgical challenges for urologists....
WOS: 000410005000021PubMed ID: 28861309Objective: For in vitro tissue engineering in urology, stem c...
The urethra is part of the lower urinary tract and its main role is urine voiding. Its complex histo...
Although urothelial progenitor-like cells have been described in the human urinary tract, the existe...
Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue ...
AbstractEngineered functional organs or tissues, created with autologous somatic cells and seeded on...
Human stem cells are promising sources for bladder regeneration. Among several possible sources, plu...
As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium...
The urothelium is a specialized epithelium covering the urinary excretory system. In case of lesions...
In vitro generation of human urothelium from stem cells would be a major advancement in the regenera...
The objective of this study was to generate bacterial cellulose (BC) scaffolds seeded with human uri...
Abstract: Human stem cells are promising sources for bladder regeneration. Among several possible so...
<div><p>Although urothelial progenitor-like cells have been described in the human urinary tract, th...
Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue ...
In order to reconstruct injured urinary tract tissues, biodegradable scaffolds with autologous seede...
Abstract BACKGROUND: Urethral reconstruction is one of the great surgical challenges for urologists....
WOS: 000410005000021PubMed ID: 28861309Objective: For in vitro tissue engineering in urology, stem c...
The urethra is part of the lower urinary tract and its main role is urine voiding. Its complex histo...
Although urothelial progenitor-like cells have been described in the human urinary tract, the existe...
Objective: For in vitro tissue engineering in urology, stem cells are commonly isolated from tissue ...
AbstractEngineered functional organs or tissues, created with autologous somatic cells and seeded on...