Background and purpose — Outcome after ligament reconstruction or tendon repair depends on secure tendon-to-bone healing. Increased osteoclastic activity resulting in local bone loss may contribute to delayed healing of the tendon–bone interface. The objective of this study was to evaluate the effect of the bisphosphonate zoledronic acid (ZA) on tendon-to-bone healing. Methods — Wistar rats (n = 92) had their right Achilles tendon cut proximally, pulled through a bone tunnel in the distal tibia and sutured anteriorly. After 1 week animals were randomized to receive a single dose of ZA (0.1 mg/kg IV) or control. Healing was evaluated at 3 and 6 weeks by mechanical testing, dual-energy X-ray absorptiometry and histology including immunohistoc...
Aim. To investigate the biomechanical effects of zoledronic acid (ZA) on femurs of female osteoporot...
The aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat o...
Drug treatment has been and will continue to be a successful method in modern medicine that can chan...
Background and purpose: Outcome after ligament reconstruction or tendon repair depends on secure ten...
WOS: 000376377700003PubMed: 26874629Objectives: This study aims to investigate the effects of zoledr...
<p>Background and purpose — Bisphosphonates are widely used in the treatment of bone loss, but they ...
Introduction: The aim of this experimental study was to evaluate the effects of systemically applied...
Numerous factors can affect skeletal regeneration, including the extent of bone injury, mechanical l...
Objective: This study aims to evaluate bone repair and the development of the medication related ost...
ABSTRACTTo investigate clinical, biomechanic and histomorphometric effects of zoledronic acid on ost...
Introduction: It has been widely assumed that osteoclasts play a pivotal role during the entire proc...
BACKGROUND: The exact pathogenesis of medication-related osteonecrosis of the jaw (MRONJ) is still...
SummaryObjectiveTo investigate the relationship between efficacy of a bisphosphonate, pain and exten...
<p>(A) Sections through the calluses (green dashed-lines) of PBS- (left) and zoledronate- (right) tr...
Objective The aim of this study was to evaluate the effects of zoledronic acid (ZA) on the cortica...
Aim. To investigate the biomechanical effects of zoledronic acid (ZA) on femurs of female osteoporot...
The aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat o...
Drug treatment has been and will continue to be a successful method in modern medicine that can chan...
Background and purpose: Outcome after ligament reconstruction or tendon repair depends on secure ten...
WOS: 000376377700003PubMed: 26874629Objectives: This study aims to investigate the effects of zoledr...
<p>Background and purpose — Bisphosphonates are widely used in the treatment of bone loss, but they ...
Introduction: The aim of this experimental study was to evaluate the effects of systemically applied...
Numerous factors can affect skeletal regeneration, including the extent of bone injury, mechanical l...
Objective: This study aims to evaluate bone repair and the development of the medication related ost...
ABSTRACTTo investigate clinical, biomechanic and histomorphometric effects of zoledronic acid on ost...
Introduction: It has been widely assumed that osteoclasts play a pivotal role during the entire proc...
BACKGROUND: The exact pathogenesis of medication-related osteonecrosis of the jaw (MRONJ) is still...
SummaryObjectiveTo investigate the relationship between efficacy of a bisphosphonate, pain and exten...
<p>(A) Sections through the calluses (green dashed-lines) of PBS- (left) and zoledronate- (right) tr...
Objective The aim of this study was to evaluate the effects of zoledronic acid (ZA) on the cortica...
Aim. To investigate the biomechanical effects of zoledronic acid (ZA) on femurs of female osteoporot...
The aim of this study was to evaluate the effect of zoledronic acid (ZA) in the ovariectomized rat o...
Drug treatment has been and will continue to be a successful method in modern medicine that can chan...