Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the brain is particularly vulnerable to oxidative stress. Induced by a redox state imbalance involving either excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system, oxidative stress plays a central role in a common pathophysiology that underpins neuronal cell death in acute neurological disorders epitomized by stroke and chronic ones such as Alzheimer’s disease. After cerebral ischemia, for example, inflammation bears a key responsibility in the development of permanent neurological damage. ROS are involved in the mechanism of post-ischemic inflammation. The activation of several inflammatory enzymes produces R...
One of the major age-related damaging agents are reactive oxygen species (ROS). The brain is more vu...
Copyright © 2013 Aurel Popa-Wagner et al. This is an open access article distributed under the Creat...
Reactive oxygen species (ROS) accumulation has been described in the brain following an ischemic ins...
Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the brain is pa...
[[abstract]]Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the...
Oxidative stress is deeply involved in various brain diseases, including neurodegenerative diseases,...
Significant amounts of oxygen free radicals (oxidants) are generated during cerebral ischemia=reperf...
Oxidative stress is associated with the pathology of acute and chronic neurodegenerative disease. Cu...
(1) Background: An important concomitant of stroke is neuroinflammation. Pomalidomide, a clinically ...
Recent evidence shows that biochemical mechanisms that occur in response to traumatic brain injury c...
Abstract: Living cells continually generate reactive oxygen species (ROS) through the respiratory ch...
We examined the neuroprotective effects of the long-acting third-generation dihydropyridine Ca2+ ant...
The rapid development of technology worldwide makes modern medicine available for more patients ever...
Plasmalogens are glycerophospholipids abundant in brain and heart tissues. Evidence suggests that th...
Oxidative stress is a pathological feature common to a multitude of neurological diseases. The produ...
One of the major age-related damaging agents are reactive oxygen species (ROS). The brain is more vu...
Copyright © 2013 Aurel Popa-Wagner et al. This is an open access article distributed under the Creat...
Reactive oxygen species (ROS) accumulation has been described in the brain following an ischemic ins...
Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the brain is pa...
[[abstract]]Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the...
Oxidative stress is deeply involved in various brain diseases, including neurodegenerative diseases,...
Significant amounts of oxygen free radicals (oxidants) are generated during cerebral ischemia=reperf...
Oxidative stress is associated with the pathology of acute and chronic neurodegenerative disease. Cu...
(1) Background: An important concomitant of stroke is neuroinflammation. Pomalidomide, a clinically ...
Recent evidence shows that biochemical mechanisms that occur in response to traumatic brain injury c...
Abstract: Living cells continually generate reactive oxygen species (ROS) through the respiratory ch...
We examined the neuroprotective effects of the long-acting third-generation dihydropyridine Ca2+ ant...
The rapid development of technology worldwide makes modern medicine available for more patients ever...
Plasmalogens are glycerophospholipids abundant in brain and heart tissues. Evidence suggests that th...
Oxidative stress is a pathological feature common to a multitude of neurological diseases. The produ...
One of the major age-related damaging agents are reactive oxygen species (ROS). The brain is more vu...
Copyright © 2013 Aurel Popa-Wagner et al. This is an open access article distributed under the Creat...
Reactive oxygen species (ROS) accumulation has been described in the brain following an ischemic ins...