Prostate cancer is the most common illness affecting men worldwide. Although much progress has been made in the study of prostate cancer prevention and treatment, less attention has been paid to the molecular mechanism of the disease. The molecular arrangement by which atractylenolide II (ATR II) induces human prostate cancer cytotoxicity was comprehensively examined in the present study. As indicated by the results, ATR II could inhibit prostate cancer cell proliferation and promote DU145 and LNCaP cell apoptosis through induced G2/M cell cycle arrest. The cell apoptosis process induced by ATR II in both DU145 and LNCaP cells was associated with its ability to inhibit androgen receptor (AR) with overexpression of protein inhibitor of activ...
Prostate cancer is one of the leading causes of death among males in the United States. In this stud...
Prostate cancer remains a leading cause of cancer death in men in the United States. Androgen depriv...
The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablat...
Abstract Background Atractylenolide I (ATR-1), an active component of Rhizoma Atractylodis Macroceph...
Androgen deprivation induces the regression of prostate tumors mainly due to an increase in the apop...
AbstractAndrogen deprivation induces the regression of prostate tumors mainly due to an increase in ...
Atractylenolide II (AT-II) exhibits several biological and pharmacological functions, especially ant...
ObjectiveTo investigate the effect of Hsp27 and the inhibitory effect of Atractylenolide I (ATL-1) o...
Atractylenolide I (ATL-1) is the major sesquiterpenoid of Atractylodes macrocephala. This study was ...
Prostate cancer is the 2nd leading cause of cancer death in American men, mainly due to therapy-resi...
Angiotensin II (Ang II), the main effector of the renin angiotensin system, acts upon two distinct t...
Prostate cancer (PC) is the most common type of cancer among men. Aggressive and metastatic PC resul...
We have previously identified a natural occurring, androgen receptor-specific antagonist. Atraric ac...
The androgen receptor (AR) is the central component in regulation of the androgen signalling within ...
International audienceAberrant androgen signaling drives prostate cancer and is targeted by drugs th...
Prostate cancer is one of the leading causes of death among males in the United States. In this stud...
Prostate cancer remains a leading cause of cancer death in men in the United States. Androgen depriv...
The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablat...
Abstract Background Atractylenolide I (ATR-1), an active component of Rhizoma Atractylodis Macroceph...
Androgen deprivation induces the regression of prostate tumors mainly due to an increase in the apop...
AbstractAndrogen deprivation induces the regression of prostate tumors mainly due to an increase in ...
Atractylenolide II (AT-II) exhibits several biological and pharmacological functions, especially ant...
ObjectiveTo investigate the effect of Hsp27 and the inhibitory effect of Atractylenolide I (ATL-1) o...
Atractylenolide I (ATL-1) is the major sesquiterpenoid of Atractylodes macrocephala. This study was ...
Prostate cancer is the 2nd leading cause of cancer death in American men, mainly due to therapy-resi...
Angiotensin II (Ang II), the main effector of the renin angiotensin system, acts upon two distinct t...
Prostate cancer (PC) is the most common type of cancer among men. Aggressive and metastatic PC resul...
We have previously identified a natural occurring, androgen receptor-specific antagonist. Atraric ac...
The androgen receptor (AR) is the central component in regulation of the androgen signalling within ...
International audienceAberrant androgen signaling drives prostate cancer and is targeted by drugs th...
Prostate cancer is one of the leading causes of death among males in the United States. In this stud...
Prostate cancer remains a leading cause of cancer death in men in the United States. Androgen depriv...
The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablat...