Hepatoblastoma (HB), a primary liver tumor of childhood, is often accompanied by raised levels of alpha-fetoprotein (α-FP). Rarely, the beta-human chorionic gonadotropin (β-hCG) levels may also be elevated, which can cause peripheral precocious puberty (PPP). We report a case of HB with precocious puberty wherein hormonal assays showed an increase in α-FP, β-hCG, and testosterone levels, and suppression of follicle-stimulating and luteinizing hormone levels. After chemotherapy and surgery, α-FP, β-hCG, and testosterone levels normalized, and the signs of virilization did not progress further. New therapeutic approaches have made a previously reported grim prognosis of virilizing HB, more favorable now. In the assessment of PPP, the possibil...
In males, precocious puberty (PP) is defined as the development of secondary sexual characteristics ...
Puberty is a complex, coordinated biological process with multiple levels of regulations. The timing...
The article is devoted to the problem of central precocious puberty — one of the orphan diseases. Th...
A 15-month old boy presented with an abdominal swelling and early development of secondary sexual ch...
A 15-month old boy presented with an abdominal swelling and early development of secondary sexual ch...
A 36-year-old woman presented with sudden abdominal pain and vomiting. Computed tomography showed a ...
Precocious puberty refers to appearance of secondary sexual characteristics, increased growth rate a...
A boy aged 7.5 years presented with precocious onset of secondary sexual characteristics and symptom...
Copyright © 2014 Irappa Madabhavi et al. This is an open access article distributed under the Creati...
Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are ...
BACKGROUND: Adrenocortical tumors (ACTs) represent less than 0.2% of all childhood neoplasms. Fr...
Leydig cell testicular tumors are a rare cause of precocious pseudopuberty in boys. Surgery is the m...
Sexual precocity in boys is defined as any sign of secondary sexual characteristics present before t...
Wilms tumor is the most frequent pediatric renal malignancy, and its usual presentation is an abdomi...
Precocious puberty is defined as the appearance of clinical signs of puberty before the age of 8 yea...
In males, precocious puberty (PP) is defined as the development of secondary sexual characteristics ...
Puberty is a complex, coordinated biological process with multiple levels of regulations. The timing...
The article is devoted to the problem of central precocious puberty — one of the orphan diseases. Th...
A 15-month old boy presented with an abdominal swelling and early development of secondary sexual ch...
A 15-month old boy presented with an abdominal swelling and early development of secondary sexual ch...
A 36-year-old woman presented with sudden abdominal pain and vomiting. Computed tomography showed a ...
Precocious puberty refers to appearance of secondary sexual characteristics, increased growth rate a...
A boy aged 7.5 years presented with precocious onset of secondary sexual characteristics and symptom...
Copyright © 2014 Irappa Madabhavi et al. This is an open access article distributed under the Creati...
Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are ...
BACKGROUND: Adrenocortical tumors (ACTs) represent less than 0.2% of all childhood neoplasms. Fr...
Leydig cell testicular tumors are a rare cause of precocious pseudopuberty in boys. Surgery is the m...
Sexual precocity in boys is defined as any sign of secondary sexual characteristics present before t...
Wilms tumor is the most frequent pediatric renal malignancy, and its usual presentation is an abdomi...
Precocious puberty is defined as the appearance of clinical signs of puberty before the age of 8 yea...
In males, precocious puberty (PP) is defined as the development of secondary sexual characteristics ...
Puberty is a complex, coordinated biological process with multiple levels of regulations. The timing...
The article is devoted to the problem of central precocious puberty — one of the orphan diseases. Th...