Multicentric Castleman's disease: Report of three cases
- M. Guazzaroni, MD PhD
- F. Bocchinfuso, MD
- E. Vasili, MD
- A. Lacchè, MD
- T. Ranalli, MD
- A. Garipoli, MD
- F. Di Tosto, MD
- R. Floris, MD PhD
DOIAbstract
Castleman's disease is an uncommon benign B-cell lymphoproliferative disorder. According to lymph nodes distribution, there are two distinct subtypes of disease: unicentric and multicentric. Unicentric Castleman's disease is more common, localized to one site, and locally treated. On the contrary, multicentric form is a rare systemic disease characterized by diffuse lymphadenopathy and inflammatory symptoms. We report three cases of persons that were initially suspected to have a lymphoma but were later histologically confirmed to have Multicentric Castleman's Disease. In addition, our work aims to investigate the role of fluorodeoxyglucose (FDG) PET/CT in evaluation of this rare condition. Keywords: Multicentric Castleman's disease, Hyalin...
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