Pregnancy outcomes among HIV-infected women who conceived on antiretroviral therapy.
- Elizabeth M Stringer
- Michelle A Kendall
- Shahin Lockman
- Thomas B Campbell
- Karin Nielsen-Saines
- Fred Sawe
- Susan Cu-Uvin
- Xingye Wu
- Judith S Currier
DOIAbstract
As antiretroviral therapy (ART) expands in resource-limited settings, understanding the impact of ART on pregnancy outcomes is critical. We analyzed women who became pregnant on ART while enrolled in a clinical trial (HPTN 052, ACTG A5208, and ACTG A5175); the majority of women were from Africa, with a median age of 29 years. Eligible women were on ART at conception and had a documented date of a last menstrual period and a pregnancy outcome. The primary outcome was non-live birth (stillbirth; spontaneous abortion; elective termination; or ectopic pregnancy) versus live birth. Preterm birth (<37 weeks completed gestation) was a secondary outcome. We used Cox proportional hazards regression models with time-varying covariates. 359 women beca...
Add to ORKG