Time trends in management of HIV-positive pregnant women in Northern Tanzania: A registry-based study.

OBJECTIVE:To examine time trends in antenatal factors and delivery characteristics in Northern Tanzania, and relate these to national guidelines for HIV in pregnancy. DESIGN:Registry-based study. SETTING:Northern Tanzania, 2000-2014. POPULATION OR SAMPLE:Deliveries (n = 33 346). METHODS:HIV-positive women were compared with HIV-negative women during four periods spanning changing national guidelines. MAIN OUTCOME MEASURES:Known maternal HIV status, HIV treatment for woman, number of antenatal care (ANC) visits, routine folate/iron in pregnancy, anemia, delivery complications/interventions. RESULTS:We observed an increase in deliveries with known maternal HIV status and women receiving HIV treatment, and a decline in deliveries with positive maternal HIV status (p-values for trend