Locke writes to Molyneux that he wants to give to the connection of ideas even more importance than he formerly did in the Essay. The study of the political and pedagogical works of Locke, and also Of the Conduct of the Understanding, contributes to extend the Lockean connection of ideas theory beyond its better-known uses (e.g. about error or the mastery of one’s passions), and it is suggested that the process of linking together and associating ideas is already effective at the very basic and biological level of human existence. Whereas ordinary and regular connection of ideas supports what we may call adaptation, several pathological associations can be described as forms of inadaptation of the living being (1), as well as of the Self (2...