Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of several pathologies including colorectal cancer (CRC). Although the adipose tissue inflammatory state is now recognized as a key player in obesity-associated morbidities, the underlying biological processes are complex and not yet precisely defined. To this end, we analyzed transcriptome profiles of human visceral adipocytes from lean and obese subjects affected or not by CRC by RNA sequencing (n = 6 subjects/category), and validated selected modulated genes by real-time qPCR. We report that obesity and CRC, conditions characterized by the common denominator of inflammation, promote changes in the transcriptional program of adipocytes mostly i...
Colorectal cancer (CRC) is among the major threatening diseases worldwide, being the third most comm...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, and the obesity-associated inflammation, represents a major risk factor for the development...
Obesity is well accepted as crucial risk factor that plays a critical role in the initiation and pro...
Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of death, with...
Objective: The aim of this study was to correlate specific fatty acid profiles of visceral white adi...
BackgroundMetabolic and transcriptomic differences between visceral adipose tissue (VAT) and subcuta...
Colorectal cancer (CRC) is among the major threatening diseases worldwide, being the third most comm...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of s...
Obesity, and the obesity-associated inflammation, represents a major risk factor for the development...
Obesity is well accepted as crucial risk factor that plays a critical role in the initiation and pro...
Colorectal cancer (CRC) is the third most common cancer worldwide and a leading cause of death, with...
Objective: The aim of this study was to correlate specific fatty acid profiles of visceral white adi...
BackgroundMetabolic and transcriptomic differences between visceral adipose tissue (VAT) and subcuta...
Colorectal cancer (CRC) is among the major threatening diseases worldwide, being the third most comm...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...
Obesity and obesity-driven cancer rates are continuing to rise worldwide. We hypothesize that adipoc...