Insectivorous bats are speculated to be ancestral hosts of Middle-East respiratory syndrome (MERS) coronavirus (CoV). MERS-CoV causes disease in humans with thirty-five percent fatality, and has evolved proteins that counteract human antiviral responses. Since bats experimentally infected with MERS-CoV do not develop signs of disease, we tested the hypothesis that MERS-CoV would replicate less efficiently in bat cells than in human cells because of its inability to subvert antiviral responses in bat cells. We infected human and bat (Eptesicus fuscus) cells with MERS-CoV and observed that the virus grew to higher titers in human cells. MERS-CoV also effectively suppressed the antiviral interferon beta (IFNβ) response in human cells, unl...
The ORF3b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has a nuclear localiza...
Abstract Background With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats...
The recent emergence of a novel human coronavirus (HCoV-EMC) in the Middle East raised considerable ...
Bats are speculated to be reservoirs of several emerging viruses including coronaviruses (CoVs) that...
Bats serve as a reservoir for various, often zoonotic viruses, including significant human pathogens...
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently isolated betacoronavirus ident...
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unkno...
The recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV), a betacoronavirus, is ...
Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans ...
Middle East respiratory syndrome coronavirus (MERS-CoV) currently spreads in humans and causes ∼36% ...
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unkno...
International audienceBats are natural reservoirs of numerous coronaviruses, including the potential...
textabstractThe recent emergence of a novel human coronavirus (HCoV-EMC) in the Middle East raised c...
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory infection wi...
Abstract Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruse...
The ORF3b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has a nuclear localiza...
Abstract Background With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats...
The recent emergence of a novel human coronavirus (HCoV-EMC) in the Middle East raised considerable ...
Bats are speculated to be reservoirs of several emerging viruses including coronaviruses (CoVs) that...
Bats serve as a reservoir for various, often zoonotic viruses, including significant human pathogens...
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently isolated betacoronavirus ident...
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unkno...
The recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV), a betacoronavirus, is ...
Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans ...
Middle East respiratory syndrome coronavirus (MERS-CoV) currently spreads in humans and causes ∼36% ...
The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unkno...
International audienceBats are natural reservoirs of numerous coronaviruses, including the potential...
textabstractThe recent emergence of a novel human coronavirus (HCoV-EMC) in the Middle East raised c...
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory infection wi...
Abstract Previous findings of Middle East Respiratory Syndrome coronavirus (MERS-CoV)-related viruse...
The ORF3b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has a nuclear localiza...
Abstract Background With the recent discovery of novel H17N10 and H18N11 influenza viral RNA in bats...
The recent emergence of a novel human coronavirus (HCoV-EMC) in the Middle East raised considerable ...