Suspected hyponatremia-induced Brugada phenocopy

Koomatie Ramsaroop,1 Rajeev Seecheran,1 Valmiki Seecheran,1 Sangeeta Persad,1 Stanley Giddings,2 Boris Mohammed,1 Naveen Anand Seecheran2 1Department of Medicine, North Central Regional Health Authority, Mt Hope, Trinidad and Tobago; 2Department of Clinical Medical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago Abstract: Brugada syndrome is a genetic condition that predisposes to an increased risk of ventricular fibrillation and sudden cardiac death in a structurally normal heart. The Brugada type 1 electrocardiogram (ECG) pattern may occur independently of the actual syndrome, and this clinical phenomenon is often referred to as Brugada phenocopy. There are several other factors which have been known to induce this electrocardiographic pattern, and currently, there is a paucity of literature with respect to the pattern that is observed in patients with electrolyte disturbances, specifically hyponatremia. This case report highlights a suspected hyponatremia-induced Brugada type 1 ECG pattern, which subsequently normalized following resolution of the electrolyte derangement. Keywords: Brugada syndrome, Brugada phenocopy, Brugada type pattern, hyponatremi