Quercetin (QUE) is a flavonoid found in several plants and commonly distributed in edible vegetables and fruits. To evaluate the effect of co-lyophilization of naproxen (NPX) with QUE at different weight ratios on physicochemical characteristics induced gastric irritation, and drug pharmacokinetics. NPX binary systems with QUE in different weight ratios were prepared by freeze-drying alkalinized solutions, and were characterized in terms of physicochemical properties as well as NPX dissolution rate in acidic pH. NPX-induced gastric inflammation studies were carried out in rats for 7 days. The pharmacokinetics of the two formulations were assessed to evaluate the bioavailability of NPX-QUE 1:2 co-lyophilizate. Westar rats were administered o...
Background & aim: In traditional medicine, medicinal plants containing flavonoid compounds were used...
Purpose: To investigate the analgesic and anti-inflammatory activities of two herbal polymedicines -...
Most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or ...
AbstractQuercetin is a major flavonoid in plant foods and potentially has beneficial effects on dise...
Quercetin is a dietary flavonoid, known to possess a range of biological properties of in in vitro s...
Copyright © 2012 Chung-Ping Yu et al. This is an open access article distributed under the Creative ...
This study investigates whether the previous observation that quercetin increases the transport of P...
Context: Diclofenac (DIC) is known for its anti-inflammatory and analgesic properties but liver toxi...
Background: Peptic ulcer is very common disease. Peptic ulcer results probably due to an imbalance b...
Naproxen and its derivative nitronaproxen at the doses of 5 and 10 mg kg-1 were compared for their a...
ABSTRACT: Naproxen and its synthesized esters namely naproxen methyl ester, C15H16O3 (compound 1), e...
The delivery of the actives through the outermost layer of the skin, the stratum corneum has posed a...
Gastrointestinal toxicity due to non-steroid anti-inflammatory rugs can be inhibited by the compound...
The purpose of this study was to evaluate the potential of micelle to change the pharmacokinetics of...
Quercetin is a dietary polyphenolic compound with potentially beneficial effects on health. Claims t...
Background & aim: In traditional medicine, medicinal plants containing flavonoid compounds were used...
Purpose: To investigate the analgesic and anti-inflammatory activities of two herbal polymedicines -...
Most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or ...
AbstractQuercetin is a major flavonoid in plant foods and potentially has beneficial effects on dise...
Quercetin is a dietary flavonoid, known to possess a range of biological properties of in in vitro s...
Copyright © 2012 Chung-Ping Yu et al. This is an open access article distributed under the Creative ...
This study investigates whether the previous observation that quercetin increases the transport of P...
Context: Diclofenac (DIC) is known for its anti-inflammatory and analgesic properties but liver toxi...
Background: Peptic ulcer is very common disease. Peptic ulcer results probably due to an imbalance b...
Naproxen and its derivative nitronaproxen at the doses of 5 and 10 mg kg-1 were compared for their a...
ABSTRACT: Naproxen and its synthesized esters namely naproxen methyl ester, C15H16O3 (compound 1), e...
The delivery of the actives through the outermost layer of the skin, the stratum corneum has posed a...
Gastrointestinal toxicity due to non-steroid anti-inflammatory rugs can be inhibited by the compound...
The purpose of this study was to evaluate the potential of micelle to change the pharmacokinetics of...
Quercetin is a dietary polyphenolic compound with potentially beneficial effects on health. Claims t...
Background & aim: In traditional medicine, medicinal plants containing flavonoid compounds were used...
Purpose: To investigate the analgesic and anti-inflammatory activities of two herbal polymedicines -...
Most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or ...