Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study

Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization.Materials and Methods: Twenty-eight sound human enamel samples were randomly divided into four groups (A-D) each having seven samples as follows: A (Novamin), B (1450 ppm NaF and Novamin), C (CPP-ACP), D (1450ppm NaF). After inducing caries-like lesions, each group was maintained daily for demineralization-remineralization cycle for seven days. During this cycle, samples were treated by the selected toothpaste for each group. Enamel mineral loss was assessed by surface microhardness. Surface enamel microhardness was determined on the enamel blocks. Non-parametric Kruskar-Wallis test compares the amount of surface microhardness recovery (SMHR%) across four different toothpastes.Results: PLM data revealed a mineral precipitation band on the surface layer of all toothpastes; however, when compared to treated lesions, no statistically significant differences among the groups (p>0.05) were found. Conclusions: NovaMin containing dentifrice has similar remineralization potential on carious-like lesions when compared to fluoride containing dentifrices