Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated autoantibody production and complement activation leading to multi-organ damage. The disease is associated with increased intestinal permeability. In this study, we tested the hypothesis that SLE subjects have increased systemic exposure to bacteria. Since bacteria induce the expression of antimicrobial response factors (ARFs), we measured the levels of a series of clinically relevant ARFs in the plasma of SLE subjects. We found that levels of sCD14, lysozyme, and CXCL16 were significantly elevated in SLE subjects. A strong positive correlation was also observed between sCD14 and SELENA-SLEDAI score. Interestingly, the ratio of EndoCAb IgM:total...
Background. Dysbiosis of gut microbiota could promote autoimmune disorders including systemic lupus ...
Intestinal dysbiosis, characterized by a reduced Firmicutes/Bacteroidetes ratio, has been reported i...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a heterogeneous course and s...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Objective – Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characte...
Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease in humans and is ...
Systemic lupus erythematosus (SLE) is a complex autoimmune disease where a loss of tolerance to nucl...
Systemic lupus erythematosus (SLE) is the prototype of autoimmune diseases with multiorgan involveme...
Comunicación presentada en la 2014 ENGIHR Conference: The Gut Microbiota Throughout Life, celebrada ...
Extensive work on experimental animal models clearly demonstrates that infectious agents can break i...
OBJECTIVES: Microbial infections and mucosal dysbiosis influence morbidity in patients with systemic...
Autoimmune diseases, such as systemic lupus erythematosus (SLE), are caused by a complex interaction...
Poster Session - Renal Pathology, Experimental Pathology, incl. Immune and Inflammatory Mechanisms -...
Background. Dysbiosis of gut microbiota could promote autoimmune disorders including systemic lupus ...
Intestinal dysbiosis, characterized by a reduced Firmicutes/Bacteroidetes ratio, has been reported i...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a heterogeneous course and s...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated aut...
Objective – Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characte...
Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease in humans and is ...
Systemic lupus erythematosus (SLE) is a complex autoimmune disease where a loss of tolerance to nucl...
Systemic lupus erythematosus (SLE) is the prototype of autoimmune diseases with multiorgan involveme...
Comunicación presentada en la 2014 ENGIHR Conference: The Gut Microbiota Throughout Life, celebrada ...
Extensive work on experimental animal models clearly demonstrates that infectious agents can break i...
OBJECTIVES: Microbial infections and mucosal dysbiosis influence morbidity in patients with systemic...
Autoimmune diseases, such as systemic lupus erythematosus (SLE), are caused by a complex interaction...
Poster Session - Renal Pathology, Experimental Pathology, incl. Immune and Inflammatory Mechanisms -...
Background. Dysbiosis of gut microbiota could promote autoimmune disorders including systemic lupus ...
Intestinal dysbiosis, characterized by a reduced Firmicutes/Bacteroidetes ratio, has been reported i...
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a heterogeneous course and s...