Rickettsial Infections and Fever, Vientiane, Laos
- Simaly Phongmany
- Jean-Marc Rolain
- Rattanaphone Phetsouvanh
- Stuart D. Blacksell
- Vimone Soukkhaseum
- Bouachanh Rasachack
- Khamphong Phiasakha
- Surn Soukkhaseum
- Khamthavi Frichithavong
- Vang Chu
- Valy Keolouangkhot
- Bertrand Martinez-Aussel
- Ko Chang
- Chirapha Darasavath
- Oudayvone Rattanavong
- Siho Sisouphone
- Mayfong Mayxay
- Sisouphane Vidamaly
- Philippe Parola
- Chanpheng Thammavong
- Mayboun Heuangvongsy
- Bounkong Syhavong
- Didier Raoult
- Nicholas J. White
- Paul N. Newton
DOIAbstract
Rickettsial diseases have not been described previously from Laos, but in a prospective study, acute rickettsial infection was identified as the cause of fever in 115 (27%) of 427 adults with negative blood cultures admitted to Mahosot Hospital in Vientiane, Laos. The organisms identified by serologic analysis were Orientia tsutsugamushi (14.8%), Rickettsia typhi (9.6%), and spotted fever group rickettsia (2.6% [8 R. helvetica, 1 R. felis, 1 R. conorii subsp. indica, and 1 Rickettsia "AT1"]). Patients with murine typhus had a lower frequency of peripheral lymphadenopathy than those with scrub typhus (3% vs. 46%, p<0.001). Rickettsioses are an underrecognized cause of undifferentiated febrile illnesses among adults in Laos. This finding has ...
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