Contagious Period for Pandemic (H1N1) 2009
- Gaston De Serres
- Isabelle Rouleau
- Marie-Eve Hamelin
- Caroline Quach
- Danuta Skowronski
- Louis Flamand
- Nicole Boulianne
- Yan Li
- Julie Carbonneau
- Anne-Marie Bourgault
- Michel Couillard
- Hugues Charest
- Guy Boivin
DOIAbstract
We estimated the proportion of persons with pandemic (H1N1) 2009 who were shedding infectious virus at diagnosis and on day 8 of illness. In households with confirmed cases, nasopharyngeal swabs were collected on all members and tested by PCR and virus culture. Of 47 cases confirmed by PCR at <7 days of illness, virus culture was positive in 92% (11/12) of febrile and 63% (22/35) of afebrile persons. Of 43 persons with PCR-confirmed pandemic (H1N1) 2009 from whom a second specimen was collected on day 8, 74% remained PCR positive and 19% were culture positive. If the 73 symptomatic household members without PCR-confirmed illness are assumed to have pandemic (H1N1) 2009, a minimum of 8% (6/73) of case-patients shed replicating virus on day 8...
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